DCTPep, the data of cancer therapy peptides.
Journal
Scientific data
ISSN: 2052-4463
Titre abrégé: Sci Data
Pays: England
ID NLM: 101640192
Informations de publication
Date de publication:
25 May 2024
25 May 2024
Historique:
received:
19
07
2023
accepted:
20
05
2024
medline:
26
5
2024
pubmed:
26
5
2024
entrez:
25
5
2024
Statut:
epublish
Résumé
With the discovery of the therapeutic activity of peptides, they have emerged as a promising class of anti-cancer agents due to their specific targeting, low toxicity, and potential for high selectivity. In particular, as peptide-drug conjugates enter clinical, the coupling of targeted peptides with traditional chemotherapy drugs or cytotoxic agents will become a new direction in cancer treatment. To facilitate the drug development of cancer therapy peptides, we have constructed DCTPep, a novel, open, and comprehensive database for cancer therapy peptides. In addition to traditional anticancer peptides (ACPs), the peptide library also includes peptides related to cancer therapy. These data were collected manually from published research articles, patents, and other protein or peptide databases. Data on drug library include clinically investigated and/or approved peptide drugs related to cancer therapy, which mainly come from the portal websites of drug regulatory authorities and organisations in different countries and regions. DCTPep has a total of 6214 entries, we believe that DCTPep will contribute to the design and screening of future cancer therapy peptides.
Identifiants
pubmed: 38796630
doi: 10.1038/s41597-024-03388-9
pii: 10.1038/s41597-024-03388-9
doi:
Substances chimiques
Peptides
0
Antineoplastic Agents
0
Peptide Library
0
Types de publication
Dataset
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
541Subventions
Organisme : National Natural Science Foundation of China (National Science Foundation of China)
ID : 82273834
Organisme : National Natural Science Foundation of China (National Science Foundation of China)
ID : 82273834
Organisme : National Natural Science Foundation of China (National Science Foundation of China)
ID : 82273834
Organisme : National Natural Science Foundation of China (National Science Foundation of China)
ID : 82273834
Organisme : National Natural Science Foundation of China (National Science Foundation of China)
ID : 82273834
Informations de copyright
© 2024. The Author(s).
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