Long-term ambient air pollution and coronary atherosclerosis: Results from the Swedish SCAPIS study.

Air pollution Atherosclerosis Cardiovascular diseases Coronary artery disease Nitrogen oxides Particulate matter

Journal

Atherosclerosis
ISSN: 1879-1484
Titre abrégé: Atherosclerosis
Pays: Ireland
ID NLM: 0242543

Informations de publication

Date de publication:
08 May 2024
Historique:
received: 03 10 2023
revised: 26 04 2024
accepted: 03 05 2024
medline: 27 5 2024
pubmed: 27 5 2024
entrez: 26 5 2024
Statut: aheadofprint

Résumé

Despite firm evidence for an association between long-term ambient air pollution exposure and cardiovascular morbidity and mortality, results from epidemiological studies on the association between air pollution exposure and atherosclerosis have not been consistent. We investigated associations between long-term low-level air pollution exposure and coronary atherosclerosis. We performed a cross-sectional analysis in the large Swedish CArdioPulmonary bioImaging Study (SCAPIS, n = 30 154), a random general population sample. Concentrations of total and locally emitted particulate matter <2.5 μm (PM Median 10-year average PM In this large, middle-aged general population sample with low exposure levels, air pollution was not associated with measures of total burden of coronary atherosclerosis. However, PM

Sections du résumé

BACKGROUND AND AIMS OBJECTIVE
Despite firm evidence for an association between long-term ambient air pollution exposure and cardiovascular morbidity and mortality, results from epidemiological studies on the association between air pollution exposure and atherosclerosis have not been consistent. We investigated associations between long-term low-level air pollution exposure and coronary atherosclerosis.
METHODS METHODS
We performed a cross-sectional analysis in the large Swedish CArdioPulmonary bioImaging Study (SCAPIS, n = 30 154), a random general population sample. Concentrations of total and locally emitted particulate matter <2.5 μm (PM
RESULTS RESULTS
Median 10-year average PM
CONCLUSIONS CONCLUSIONS
In this large, middle-aged general population sample with low exposure levels, air pollution was not associated with measures of total burden of coronary atherosclerosis. However, PM

Identifiants

DOI: 10.1016/j.atherosclerosis.2024.117576 PMID: 38797616
pubmed: 38797616
pii: S0021-9150(24)00136-9
doi: 10.1016/j.atherosclerosis.2024.117576
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

117576

Informations de copyright

Copyright © 2024 The Authors. Published by Elsevier B.V. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Auteurs

Karl Kilbo Edlund (K)

Occupational and Environmental Medicine, School of Public Health and Community Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Sweden; Department of Occupational and Environmental Medicine, Sahlgrenska University Hospital, Göteborg, Sweden. Electronic address: karl.kilbo.edlund@gu.se.

Eva M Andersson (EM)

Occupational and Environmental Medicine, School of Public Health and Community Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Sweden; Department of Occupational and Environmental Medicine, Sahlgrenska University Hospital, Göteborg, Sweden.

Christian Asker (C)

Swedish Meteorological & Hydrological Institute, Norrköping, Sweden.

Lars Barregard (L)

Occupational and Environmental Medicine, School of Public Health and Community Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Sweden; Department of Occupational and Environmental Medicine, Sahlgrenska University Hospital, Göteborg, Sweden.

Göran Bergström (G)

Department of Molecular and Clinical Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Sweden; Department of Clinical Physiology Sahlgrenska University Hospital, Göteborg, Sweden.

Kristina Eneroth (K)

SLB-analys, Environment and Health Administration, Stockholm, Sweden.

Tomas Jernberg (T)

Department of Clinical Sciences, Danderyd University Hospital, Karolinska Institutet, Stockholm, Sweden.

Stefan Ljunggren (S)

Occupational and Environmental Medicine Center, Department of Clinical and Experimental Medicine, Linköping University, Linköping, Sweden.

Peter Molnár (P)

Occupational and Environmental Medicine, School of Public Health and Community Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Sweden; Department of Occupational and Environmental Medicine, Sahlgrenska University Hospital, Göteborg, Sweden.

Johan Nilsson Sommar (JN)

Department of Public Health and Clinical Medicine, Faculty of Medicine, Umeå University, Umeå, Sweden.

Anna Oudin (A)

Department of Public Health and Clinical Medicine, Faculty of Medicine, Umeå University, Umeå, Sweden; Division of Occupational and Environmental Medicine, Department of Laboratory Medicine, Faculty of Medicine, Lund University, Sweden.

Göran Pershagen (G)

Institute of Environmental Medicine, Karolinska Institute, Stockholm, Sweden.

Åsa Persson (Å)

Institute of Environmental Medicine, Karolinska Institute, Stockholm, Sweden.

Andrei Pyko (A)

Institute of Environmental Medicine, Karolinska Institute, Stockholm, Sweden; Centre for Occupational and Environmental Medicine, Region Stockholm, Stockholm, Sweden.

Mårten Spanne (M)

Environmental Department, City of Malmö, Malmö, Sweden.

Martin Tondel (M)

Occupational and Environmental Medicine, Department of Medical Sciences, Medical Faculty, Uppsala University, Sweden; Occupational and Environmental Medicine, Uppsala University Hospital, Uppsala, Sweden.

Mikael Ögren (M)

Department of Occupational and Environmental Medicine, Sahlgrenska University Hospital, Göteborg, Sweden.

Petter Ljungman (P)

Institute of Environmental Medicine, Karolinska Institute, Stockholm, Sweden; Department of Cardiology, Danderyd Hospital, Stockholm, Sweden.

Leo Stockfelt (L)

Occupational and Environmental Medicine, School of Public Health and Community Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Sweden; Department of Occupational and Environmental Medicine, Sahlgrenska University Hospital, Göteborg, Sweden.

Classifications MeSH