Quantitative and systematic NMR measurements of sequence-dependent A-T Hoogsteen dynamics uncovers unique conformational specificity in the DNA double helix.
Journal
bioRxiv : the preprint server for biology
Titre abrégé: bioRxiv
Pays: United States
ID NLM: 101680187
Informations de publication
Date de publication:
15 May 2024
15 May 2024
Historique:
medline:
27
5
2024
pubmed:
27
5
2024
entrez:
27
5
2024
Statut:
epublish
Résumé
The propensities to form lowly-populated short-lived conformations of DNA could vary with sequence, providing an important source of sequence-specificity in biochemical reactions. However, comprehensively measuring how these dynamics vary with sequence is challenging. Using
Identifiants
pubmed: 38798635
doi: 10.1101/2024.05.15.594415
pmc: PMC11118333
pii:
doi:
Types de publication
Preprint
Langues
eng