Genetic architecture of disease resistance and tolerance in Douglas-fir trees.
Douglas‐fir
GWAS
climate change
disease resistance
fungal pathogens
local adaptation
temperate trees
Journal
The New phytologist
ISSN: 1469-8137
Titre abrégé: New Phytol
Pays: England
ID NLM: 9882884
Informations de publication
Date de publication:
27 May 2024
27 May 2024
Historique:
received:
04
01
2024
accepted:
18
03
2024
medline:
28
5
2024
pubmed:
28
5
2024
entrez:
28
5
2024
Statut:
aheadofprint
Résumé
Understanding the genetic basis of how plants defend against pathogens is important to monitor and maintain resilient tree populations. Swiss needle cast (SNC) and Rhabdocline needle cast (RNC) epidemics are responsible for major damage of forest ecosystems in North America. Here we investigate the genetic architecture of tolerance and resistance to needle cast diseases in Douglas-fir (Pseudotsuga menziesii) caused by two fungal pathogens: SNC caused by Nothophaeocryptopus gaeumannii, and RNC caused by Rhabdocline pseudotsugae. We performed case-control genome-wide association analyses and found disease resistance and tolerance in Douglas-fir to be polygenic and under strong selection. We show that stomatal regulation as well as ethylene and jasmonic acid pathways are important for resisting SNC infection, and secondary metabolite pathways play a role in tolerating SNC once the plant is infected. We identify a major transcriptional regulator of plant defense, ERF1, as the top candidate for RNC resistance. Our findings shed light on the highly polygenic architectures underlying fungal disease resistance and tolerance and have important implications for forestry and conservation as the climate changes.
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : Genome Canada
ID : 241REF
Organisme : Genome BC
Organisme : Genome Alberta
Organisme : Génome Québec
Organisme : BC Ministry of Forests
Organisme : Alberta Innovates Bio Solutions
Organisme : Vernon Seed Orchard Company
Organisme : University of Alberta
Organisme : University of British Columbia
Organisme : Digital Research Alliance of Canada
Organisme : Mosaic Forest Management
Organisme : Western Forest Products
Organisme : NSERC
Organisme : US Forest Service
Informations de copyright
© 2024 The Authors. New Phytologist © 2024 New Phytologist Foundation.
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