Sexual satisfaction and its predictors in patients with advanced cancer and their family caregivers in six European countries: Baseline data from the DIAdIC study.
advanced cancer
cross‐sectional survey
family caregivers
psycho‐oncology
sexual satisfaction
Journal
Psycho-oncology
ISSN: 1099-1611
Titre abrégé: Psychooncology
Pays: England
ID NLM: 9214524
Informations de publication
Date de publication:
Jun 2024
Jun 2024
Historique:
revised:
11
04
2024
received:
02
02
2024
accepted:
06
05
2024
medline:
28
5
2024
pubmed:
28
5
2024
entrez:
28
5
2024
Statut:
ppublish
Résumé
To identify predictors of sexual satisfaction in patients with advanced cancer and their family caregivers. Cross-sectional study using baseline survey data from a randomized controlled trial in six European countries. Patients with advanced cancer and their family caregiver completed measures on sexual satisfaction (one item from Functional Assessment of Cancer Therapy - General questionnaire for patients and Caregiver Quality of Life Index-Cancer scale for family caregivers) and health-related characteristics. Multivariable linear regressions were performed for all predictors (identified based on literature) with sexual satisfaction as dependent variable. The sample comprised 431 patient-family caregiver dyads. Patients with prostate or gynecological cancer reported lower sexual satisfaction (respectively B = -0.267 95% CI: -1.674, -0.594 and B = -0.196, 95% CI -2.103, -0.452). Higher emotional (B = 0.278, 95% CI 0.024, 0.057) physical (B = 0.305, 95% CI 0.012, 0.025) and social functioning (B = 0.151, 95% CI 0.001, 0.013), global health (B = 0.356, 95% CI 0.007, 0.013) and social wellbeing (B = 0.161, 95% CI 0.013, 0.082) among patients were associated with higher sexual satisfaction. Among family caregivers, sexual satisfaction was lower with increased age (B = -0.142, 95% CI -0.022, -0.004). Higher emotional functioning (B = 0.027, 95% CI 0.011, 0.043) and quality of life (B = 0.165, 95% CI -0.165, 0.716) were associated with higher sexual satisfaction in family caregivers. The results underscore that sexual wellbeing of patients and family caregivers is related to health related factors in physical, emotional, and social domains. Patients and family caregivers could benefit from a dyadic approach to address sexual wellbeing.
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
e6347Subventions
Organisme : European Commission
ID : 825722
Investigateurs
Aline De Vleminck
(A)
Joachim Cohen
(J)
Kim Eecloo
(K)
Vincent Renard
(V)
Jurgen De Groote
(J)
Nele Lobbestael
(N)
Helle Pappot
(H)
Lisa Sengeløv
(L)
Mogens Grønvold
(M)
Katherine Bristowe
(K)
Agnes van der Heide
(A)
Maaike van der Wel
(M)
Elena Turola
(E)
Chiara Puglisi
(C)
Federica Sforacchi
(F)
Valeria Soffientini
(V)
Stefania Tortella
(S)
Silvia Zini
(S)
Kevin Brazil
(K)
Joanne Reid
(J)
Gillian Prue
(G)
Charles Normand
(C)
Peter May
(P)
Suzanne Guerin
(S)
Paul D'Alton
(P)
Monika Pilch
(M)
Phil Larkin
(P)
Informations de copyright
© 2024 John Wiley & Sons Ltd.
Références
Mercadante S, Vitrano V, Catania V. Sexual issues in early and late stage cancer: a review. Support Care Cancer. 2010;18(6):659‐665. https://doi.org/10.1007/s00520‐010‐0814‐0
Hughes MK. Sexuality and the cancer survivor: a silent coexistence. Cancer Nurs. 2000;23(6):477‐482. https://doi.org/10.1097/00002820‐200012000‐00011
Berterö C, Chamberlain WM. Breast cancer diagnosis and its treatment affecting the self: a meta‐synthesis. Cancer Nurs. 2007;30(3):194‐202. https://doi.org/10.1097/01.ncc.0000270707.80037.4c
Archibald S, Lemieux S, Byers ES, Tamlyn K, Worth J. Chemically‐induced menopause and the sexual functioning of breast cancer survivors. Women Ther. 2006;29(1–2):83‐106. https://doi.org/10.1300/j015v29n01_05
Arora NK, Gustafson DH, Hawkins RP, et al. Impact of surgery and chemotherapy on the quality of life of younger women with breast carcinoma: a prospective study. Cancer. 2001;92(5):1288‐1298. https://doi.org/10.1002/1097‐0142(20010901)92:5<1288::aid‐cncr1450>3.0.co;2‐e
Mulhall JP. Defining and reporting erectile function outcomes after radical prostatectomy: challenges and misconceptions. J Urol. 2009;181(2):462‐471. https://doi.org/10.1016/j.juro.2008.10.047
Frey A, Sønksen J, Jakobsen H, Fode M. Prevalence and predicting factors for commonly neglected sexual side effects to radical prostatectomies: results from a cross‐sectional questionnaire‐based study. J Sex Med [Internet]. 2014;11(9):2318‐2326. https://doi.org/10.1111/jsm.12624
Böhm G, Kirschner‐Hermanns R, Decius A, Heussen N, Schumpelick V, Willis S. Anorectal, bladder, and sexual function in females following colorectal surgery for carcinoma. Int J Colorectal Dis [Internet]. 2008;23(9):893‐900. https://doi.org/10.1007/s00384‐008‐0498‐9
Hodges LJ, Humphris GM, Macfarlane G. A meta‐analytic investigation of the relationship between the psychological distress of cancer patients and their carers. Soc Sci Med. 2005;60(1):1‐12. https://doi.org/10.1016/j.socscimed.2004.04.018
Badr H, Carmack Taylor CL. Sexual dysfunction and spousal communication in couples coping with prostate cancer. Psychooncology [Internet]. 2009;18(7):735‐746. https://doi.org/10.1002/pon.1449
Loaring JM, Larkin M, Shaw R, Flowers P. Renegotiating Sexual Intimacy in the Context of Altered Embodiment: The Experiences of Women with Breast Cancer and Their Male Partners Following Mastectomy and Reconstruction. Health Psychol. 2015;34:426‐436. Health Psychology. Larkin, Michael: School of Psychology, University of Birmingham, Edgbaston, Birmingham, United Kingdom, B15 2TT, m.larkin@bham.ac.uk, American Psychological Association. https://doi.org/10.1037/hea0000195
Seigal J. Counselling people with disabilities/chronic illnesses. In: Palmer S, McMahon G, eds. Handbook of Counselling. 2nd ed. Routledge; 1997.
Milbury K, Badr H. Sexual problems, communication patterns, and depressive symptoms in couples coping with metastatic breast cancer. Psychooncology [Internet]. 2013;22(4):814‐822. Available from:. https://doi.org/10.1002/pon.3079
Nelson CJ, Choi JM, Mulhall JP, Roth AJ. Determinants of sexual satisfaction in men with prostate cancer. J Sex Med. 2007;4(5):1422‐1427. https://doi.org/10.1111/j.1743‐6109.2007.00547.x
Mütsch J, Friedrich M, Leuteritz K, et al. Sexuality and cancer in adolescents and young adults ‐ a comparison between reproductive cancer patients and patients with non‐reproductive cancer. BMC Cancer. 2019;19(1):1‐13. https://doi.org/10.1186/s12885‐019‐6009‐2
Love AW, Scealy M, Bloch S, et al. Psychosocial adjustment in newly diagnosed prostate cancer. Aust N Z J Psychiatry. 2008;42(5):423‐429. https://doi.org/10.1080/00048670801961081
Gini G, Cimminiello M, Galieni P, et al. Advanced stage hodgkin lymphoma: patient management. Acta Biomed. 2020;91(S‐5):5‐12.
Matthys O, De Vleminck A, Dierickx S, et al. Effectiveness of a nurse‐delivered (FOCUS+) and a web‐based (iFOCUS) psychoeducational intervention for people with advanced cancer and their family caregivers (DIAdIC): study protocol for an international randomized controlled trial. BMC Palliat Care [Internet]. 2021;20(1):1‐18. Available from. https://doi.org/10.1186/s12904‐021‐00895‐z
Carmack Taylor CL, Basen‐Engquist K, Shinn EH, Bodurka DC. Predictors of sexual functioning in ovarian cancer patients. J Clin Oncol Off J Am Soc Clin Oncol. 2004;22(5):881‐889. https://doi.org/10.1200/jco.2004.08.150
Garos S, Kluck A, Aronoff D. Prostate cancer patients and their partners: differences in satisfaction indices and psychological variables. J Sex Med. 2007;4(5):1394‐1403. https://doi.org/10.1111/j.1743‐6109.2007.00545.x
Cella BDF, Tulsky DS, Gray G, et al. The functional assessment of cancer Therapy scale: development and validation of the general measure. J Clin Oncol. 1993;11(3):570‐579. https://doi.org/10.1200/jco.1993.11.3.570
Weitzner MA, Jacobsen PB, Wagner H, Friedland J, Cox C. The Caregiver Quality of Life Index‐Cancer (CQOLC) scale: development and validation of an instrument to measure quality of life of the family caregiver of patients with cancer. Qual Life Res. 1999;8(1–2):55‐63. https://doi.org/10.1023/a:1026407010614
Hagedoorn M, Kuijer RG, Buunk BP, DeJong GM, Wobbes T, Sanderman R. Marital satisfaction in patients with cancer: does support from intimate partners benefit those who need it the most? Heal Psychol Off J Div Heal Psychol Am Psychol Assoc. 2000;19(3):274‐282. https://doi.org/10.1037/0278‐6133.19.3.274
Groenvold M, Petersen MA, Aaronson NK, et al. The development of the EORTC QLQ‐C15‐PAL: a shortened questionnaire for cancer patients in palliative care. Eur J Cancer. 2006;42(1):55‐64. https://doi.org/10.1016/j.ejca.2005.06.022
Aaronson NK, Ahmedzai S, Bergman B, et al. The European organization for research and treatment of cancer qlq‐C30: a quality‐of‐life instrument for use in international clinical trials in oncology. JNCI J Natl Cancer Inst [Internet]. 1993;85(5):365‐376. Available from. https://doi.org/10.1093/jnci/85.5.365
Carver CS. You want to measure coping but your protocol’s too long: consider the brief COPE. Int J Behav Med. 1997;4(1):92‐100. https://doi.org/10.1207/s15327558ijbm0401_6
Levesque C, Lafontaine MF, Caron A, Fitzpatrick J. Validation of the English version of the dyadic coping inventory. Meas Eval Couns Dev. 2014;47(3):215‐225. https://doi.org/10.1177/0748175614522272
von Elm E, Altman DG, Egger M, Pocock SJ, Gøtzsche PC, Vandenbroucke JP. The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) statement: guidelines for reporting observational studies. J Clin Epidemiol. 2008;61(4):344‐349. https://doi.org/10.1016/j.jclinepi.2007.11.008
Yildiz Y, Alacacıoğlu A, Varol U, et al. Evaluating sexual satisfaction and quality of life in patients with gynecological cancer. Acta Oncol Turc. 2018;51(3):370‐376. https://doi.org/10.5505/aot.2018.04834
Stead ML, Fallowfield L, Selby P, Brown JM. Psychosexual function and impact of gynaecological cancer. Best Pract Res Clin Obstet Gynaecol. 2007;21(2):309‐320. https://doi.org/10.1016/j.bpobgyn.2006.11.008
Letts C, Tamlyn K, Byers ES. Exploring the impact of prostate cancer on men’s sexual well‐being. J Psychosoc Oncol. 2010;28(5):490‐510. https://doi.org/10.1080/07347332.2010.498457
Cheung YB, Daniel R, Ng GY. Response and non‐response to a quality‐of‐life question on sexual life: a case study of the simple mean imputation method. Qual Life Res [Internet]. 2006;15(9):1493‐1501. https://doi.org/10.1007/s11136‐006‐0004‐1
Santos‐Iglesias P, Sierra J, García M, Martínez A, Sánchez A, Tapia MI. Index of Sexual Satisfaction (ISS): a study on the reliability and validity. Int J Psychol Psychol Ther. 2009;9:259‐273.
Li M, Chan CWH, Chow KM, Xiao J, Choi KC. A systematic review and meta‐analysis of couple‐based intervention on sexuality and the quality of life of cancer patients and their partners. Support Care Cancer. 2020;28(4):1607‐1630. https://doi.org/10.1007/s00520‐019‐05215‐z
Li Q, Loke AY. A systematic review of spousal couple‐based intervention studies for couples coping with cancer: direction for the development of interventions. Psycho Oncol. 2014;23(7):731‐739. https://doi.org/10.1002/pon.3535
Rothman KJ, Gallacher JEJ, Hatch EE. Why representativeness should be avoided. Int J Epidemiol. 2013;42(4):1012‐1014. https://doi.org/10.1093/ije/dys223
Hawkins Y, Ussher J, Gilbert E, Perz J, Sandoval M, Sundquist K. Changes in sexuality and intimacy after the diagnosis and treatment of cancer: the experience of partners in a sexual relationship with a person with cancer. Cancer Nurs [Internet]. 2009;32(4):271‐280. https://doi.org/10.1097/ncc.0b013e31819b5a93
Miaja M, Platas A, Martinez‐Cannon BA. Psychological impact of alterations in sexuality, fertility, & body image in young breast cancer patients & their partners. Rev Investig Clin. 2017;69(4):204‐209. https://doi.org/10.24875/ric.17002279
Traa MJ, De Vries J, Roukema JA, Rutten HJT, Den Oudsten BL. The sexual health care needs after colorectal cancer: the view of patients, partners, and health care professionals. Support Care Cancer. 2014;22(3):763‐772. https://doi.org/10.1007/s00520‐013‐2032‐z