Challenges in assessing the immunization status of adults in Germany-lessons from a population-based VACCELERATE survey on polio vaccination.

Infection control Pandemic preparedness Public health Surveillance Vaccination coverage Vaccine preventable

Journal

Infection
ISSN: 1439-0973
Titre abrégé: Infection
Pays: Germany
ID NLM: 0365307

Informations de publication

Date de publication:
28 May 2024
Historique:
received: 14 02 2024
accepted: 13 05 2024
medline: 29 5 2024
pubmed: 29 5 2024
entrez: 28 5 2024
Statut: aheadofprint

Résumé

Considering the re-emergence of poliomyelitis (PM) in non-endemic regions, it becomes apparent that vaccine preventable diseases can rapidly develop epi- or even pandemic potential. Evaluation of the current vaccination status is required to inform patients, health care providers and policy makers about vaccination gaps. Between October 28 2022 and November 23 2022, 5,989 adults from the VACCELEREATE Volunteer Registry completed an electronic case report form on their previous PM vaccine doses including number, types/-valencies and the time of administration based on their vaccination records. A uni-/multivariable regression analysis was performed to assess associations in participant characteristics and immunization status. Among German volunteers (n = 5,449), complete PM immunization schedule was found in 1,981 (36%) participants. Uncertain immunization, due to unknown previous PM vaccination (n = 313, 6%), number of doses (n = 497, 9%), types/-valencies (n = 1,233, 23%) or incoherent immunization schedule (n = 149, 3%) was found in 40% (n = 2,192). Out of 1,276 (23%) participants who reported an incomplete immunization schedule, 62 (1%) never received any PM vaccine. A total of 5,074 (93%) volunteers reported having been vaccinated at least once and 2,087 (38%) indicated that they received vaccination within the last ten years. Female sex, younger age, as well as availability of first vaccination record were characteristics significantly associated with complete immunization (p < 0.001). Full PM immunization schedule was low and status frequently classified as uncertain due to lack of details on administered doses. There is an obviousneed for improved recording to enable long-term access to detailed vaccination history in the absence of a centralized immunization register.

Identifiants

pubmed: 38806974
doi: 10.1007/s15010-024-02296-9
pii: 10.1007/s15010-024-02296-9
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Informations de copyright

© 2024. The Author(s).

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Auteurs

Julia A Nacov (JA)

Faculty of Medicine, Institute of Translational Research, University of CologneUniversity Hospital CologneCologne Excellence Cluster On Cellular Stress Responses in Aging-Associated Diseases (CECAD), Herderstr. 52-54, 50931, Cologne, Germany.
Faculty of Medicine, Department I of Internal Medicine, Excellence Center for Medical Mycology (ECMM), University of Cologne, and University Hospital Cologne, Cologne, Germany.
German Centre for Infection Research (DZIF), Partner Site Bonn-Cologne, Cologne, Germany.

Jannik Stemler (J)

Faculty of Medicine, Institute of Translational Research, University of CologneUniversity Hospital CologneCologne Excellence Cluster On Cellular Stress Responses in Aging-Associated Diseases (CECAD), Herderstr. 52-54, 50931, Cologne, Germany.
Faculty of Medicine, Department I of Internal Medicine, Excellence Center for Medical Mycology (ECMM), University of Cologne, and University Hospital Cologne, Cologne, Germany.
German Centre for Infection Research (DZIF), Partner Site Bonn-Cologne, Cologne, Germany.

Jon Salmanton-García (J)

Faculty of Medicine, Institute of Translational Research, University of CologneUniversity Hospital CologneCologne Excellence Cluster On Cellular Stress Responses in Aging-Associated Diseases (CECAD), Herderstr. 52-54, 50931, Cologne, Germany.
Faculty of Medicine, Department I of Internal Medicine, Excellence Center for Medical Mycology (ECMM), University of Cologne, and University Hospital Cologne, Cologne, Germany.
German Centre for Infection Research (DZIF), Partner Site Bonn-Cologne, Cologne, Germany.

Louise M Cremer (LM)

Faculty of Medicine, Institute of Translational Research, University of CologneUniversity Hospital CologneCologne Excellence Cluster On Cellular Stress Responses in Aging-Associated Diseases (CECAD), Herderstr. 52-54, 50931, Cologne, Germany.
Faculty of Medicine, Department I of Internal Medicine, Excellence Center for Medical Mycology (ECMM), University of Cologne, and University Hospital Cologne, Cologne, Germany.
German Centre for Infection Research (DZIF), Partner Site Bonn-Cologne, Cologne, Germany.

Markus Zeitlinger (M)

Department of Clinical Pharmacology, Medical University of Vienna, Vienna, Austria.

Patrick W G Mallon (PWG)

School of Medicine, University College Dublin, Centre for Experimental Pathogen Host Research, Dublin, Ireland.

Zoi Dorothea Pana (ZD)

Medical School, European University Cyprus (EUC), Nicosia, Cyprus.

Heinz-Josef Schmitt (HJ)

Faculty of Medicine, Institute of Translational Research, University of CologneUniversity Hospital CologneCologne Excellence Cluster On Cellular Stress Responses in Aging-Associated Diseases (CECAD), Herderstr. 52-54, 50931, Cologne, Germany.
Faculty of Medicine, Department I of Internal Medicine, Excellence Center for Medical Mycology (ECMM), University of Cologne, and University Hospital Cologne, Cologne, Germany.
German Centre for Infection Research (DZIF), Partner Site Bonn-Cologne, Cologne, Germany.

Oliver A Cornely (OA)

Faculty of Medicine, Institute of Translational Research, University of CologneUniversity Hospital CologneCologne Excellence Cluster On Cellular Stress Responses in Aging-Associated Diseases (CECAD), Herderstr. 52-54, 50931, Cologne, Germany. oliver.cornely@uk-koeln.de.
Faculty of Medicine, Department I of Internal Medicine, Excellence Center for Medical Mycology (ECMM), University of Cologne, and University Hospital Cologne, Cologne, Germany. oliver.cornely@uk-koeln.de.
German Centre for Infection Research (DZIF), Partner Site Bonn-Cologne, Cologne, Germany. oliver.cornely@uk-koeln.de.
Faculty of Medicine, University of Cologne, University Hospital Cologne, Clinical Trials Centre Cologne (ZKS Köln), Cologne, Germany. oliver.cornely@uk-koeln.de.

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