Seroepidemiology of
Antibody
Toxoplasma gondii
diabetes
enzyme-linked immunosorbent assay
Journal
Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences
ISSN: 1735-1995
Titre abrégé: J Res Med Sci
Pays: India
ID NLM: 101235599
Informations de publication
Date de publication:
2024
2024
Historique:
received:
21
01
2023
revised:
11
03
2023
accepted:
18
05
2023
medline:
29
5
2024
pubmed:
29
5
2024
entrez:
29
5
2024
Statut:
epublish
Résumé
Type 2 diabetes mellitus (T2DM) is prone to opportunistic infections, including toxoplasmosis, due to an immunodeficiency system. This study aimed to evaluate the serum of people with T2DM to determine the titer of anti-toxoplasma antibodies in patients and compare it with the control group. 720 blood samples have been carried out between October and the end of January 2017 in Sistan, and Baluchestan provinces in southeastern Iran, of these, 360 samples were related to healthy individuals (control), and 360 samples were related to T2DM individuals. The immunoglobulin (Ig) M and IgG enzyme-linked immunosorbent assay methods have been used to detect toxoplasmosis. The data were analyzed using SPSS-19, Chi-square, and Fisher's exact test to compare statistical parameters. In this cross-sectional study, out of 360 samples of T2DM by ELISA method, 60% samples in diabetic patients and 48.1% in control group were IgG positive ( Anti-toxoplasma antibodies including IgG and IgM were higher in diabetic patient in comparison to control group.
Sections du résumé
Background
UNASSIGNED
Type 2 diabetes mellitus (T2DM) is prone to opportunistic infections, including toxoplasmosis, due to an immunodeficiency system. This study aimed to evaluate the serum of people with T2DM to determine the titer of anti-toxoplasma antibodies in patients and compare it with the control group.
Materials and Methods
UNASSIGNED
720 blood samples have been carried out between October and the end of January 2017 in Sistan, and Baluchestan provinces in southeastern Iran, of these, 360 samples were related to healthy individuals (control), and 360 samples were related to T2DM individuals. The immunoglobulin (Ig) M and IgG enzyme-linked immunosorbent assay methods have been used to detect toxoplasmosis. The data were analyzed using SPSS-19, Chi-square, and Fisher's exact test to compare statistical parameters.
Results
UNASSIGNED
In this cross-sectional study, out of 360 samples of T2DM by ELISA method, 60% samples in diabetic patients and 48.1% in control group were IgG positive (
Conclusion
UNASSIGNED
Anti-toxoplasma antibodies including IgG and IgM were higher in diabetic patient in comparison to control group.
Identifiants
pubmed: 38808216
doi: 10.4103/jrms.jrms_49_23
pii: JRMS-29-19
pmc: PMC11132423
doi:
Types de publication
Journal Article
Langues
eng
Pagination
19Informations de copyright
Copyright: © 2024 Journal of Research in Medical Sciences.
Déclaration de conflit d'intérêts
The authors declared no conceivable conflicts of activity concerning the research, authorship, and/or e-book of this article.