Investigating the effect of Aloe vera on the prevention and treatment of radiotherapy-induced oral mucositis in patients with head-and-neck cancer.
Aloe vera
head-and-neck cancer
oral mucositis
radiotherapy
Journal
Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences
ISSN: 1735-1995
Titre abrégé: J Res Med Sci
Pays: India
ID NLM: 101235599
Informations de publication
Date de publication:
2024
2024
Historique:
received:
19
02
2023
revised:
31
08
2023
accepted:
14
11
2023
medline:
29
5
2024
pubmed:
29
5
2024
entrez:
29
5
2024
Statut:
epublish
Résumé
Oral mucositis is one of the main complications of radiotherapy (RT) while treating head-and-neck cancers and can affect the patients' treatment process and life. Therefore, this study evaluated the effect of Aloe vera on the prevention and treatment of radiotherapy-induced oral mucositis (RIOM) in patients with head-and-neck cancer. This was a double-blind clinical trial performed in 2019 on 75 patients with head-and-neck cancer. Patients were randomly assigned to two groups receiving gargles of 5 cc Aloe vera and the same dose of placebo mouthwash three times a day, respectively. Then, the incidence and severity of RIOM were evaluated and compared between the two groups over 6 weeks of RT. There was no significant difference between the two groups in terms of the severity of RIOM from the 1 According to the results of the present study, the long-term use of Aloe vera mouthwash can reduce the severity of RIOM.
Sections du résumé
Background
UNASSIGNED
Oral mucositis is one of the main complications of radiotherapy (RT) while treating head-and-neck cancers and can affect the patients' treatment process and life. Therefore, this study evaluated the effect of Aloe vera on the prevention and treatment of radiotherapy-induced oral mucositis (RIOM) in patients with head-and-neck cancer.
Materials and Methods
UNASSIGNED
This was a double-blind clinical trial performed in 2019 on 75 patients with head-and-neck cancer. Patients were randomly assigned to two groups receiving gargles of 5 cc Aloe vera and the same dose of placebo mouthwash three times a day, respectively. Then, the incidence and severity of RIOM were evaluated and compared between the two groups over 6 weeks of RT.
Results
UNASSIGNED
There was no significant difference between the two groups in terms of the severity of RIOM from the 1
Conclusion
UNASSIGNED
According to the results of the present study, the long-term use of Aloe vera mouthwash can reduce the severity of RIOM.
Identifiants
pubmed: 38808218
doi: 10.4103/jrms.jrms_115_23
pii: JRMS-29-16
pmc: PMC11132420
doi:
Types de publication
Journal Article
Langues
eng
Pagination
16Informations de copyright
Copyright: © 2024 Journal of Research in Medical Sciences.
Déclaration de conflit d'intérêts
There are no conflicts of interest.