Distribution and predictors of F-18-FDG uptake values of non-malignant cervical lymph nodes in pediatric patients.
Cervical lymph nodes
Children
Deauville score
Positron emission tomography
Tonsil
Journal
EJNMMI research
ISSN: 2191-219X
Titre abrégé: EJNMMI Res
Pays: Germany
ID NLM: 101560946
Informations de publication
Date de publication:
29 May 2024
29 May 2024
Historique:
received:
05
03
2024
accepted:
03
05
2024
medline:
29
5
2024
pubmed:
29
5
2024
entrez:
29
5
2024
Statut:
epublish
Résumé
F-18-flurodeoxyglucose (FDG) PET/CT is routinely used for staging, evaluation of response to treatment and follow-up of most pediatric malignancies. Cervical lymph nodes can be involved in some pediatric malignancies, but increased uptake in non-malignant cervical lymph nodes is not exceptional in this population. The aim of the present study is to identify predictors of the maximum uptake in non-malignant cervical lymph nodes in the pediatric population. 191 FDG PET/CT studies of pediatric patients without malignant involvement of cervical lymph nodes were retrospectively reviewed. The maximal Standard Uptake Value in the hottest cervical lymph node (SUVmax Increased FDG activity in cervical nodes was observed in 136/191 studies (71%). The mean SUVmax SUVmax in ipsilateral palatine tonsil is a strong predictor of the maximal uptake value of non-malignant cervical lymph nodes in children. The intensity of uptake in non-malignant cervical lymph nodes is frequently higher than liver uptake in children, and this tendency increases for younger patients. In the internal hospital registry under TRN 0209-22-HMO on date 23.04.2022.
Sections du résumé
BACKGROUND
BACKGROUND
F-18-flurodeoxyglucose (FDG) PET/CT is routinely used for staging, evaluation of response to treatment and follow-up of most pediatric malignancies. Cervical lymph nodes can be involved in some pediatric malignancies, but increased uptake in non-malignant cervical lymph nodes is not exceptional in this population. The aim of the present study is to identify predictors of the maximum uptake in non-malignant cervical lymph nodes in the pediatric population.
METHODS
METHODS
191 FDG PET/CT studies of pediatric patients without malignant involvement of cervical lymph nodes were retrospectively reviewed. The maximal Standard Uptake Value in the hottest cervical lymph node (SUVmax
RESULTS
RESULTS
Increased FDG activity in cervical nodes was observed in 136/191 studies (71%). The mean SUVmax
CONCLUSION
CONCLUSIONS
SUVmax in ipsilateral palatine tonsil is a strong predictor of the maximal uptake value of non-malignant cervical lymph nodes in children. The intensity of uptake in non-malignant cervical lymph nodes is frequently higher than liver uptake in children, and this tendency increases for younger patients.
TRIAL WAS REGISTERED
UNASSIGNED
In the internal hospital registry under TRN 0209-22-HMO on date 23.04.2022.
Identifiants
pubmed: 38809472
doi: 10.1186/s13550-024-01110-9
pii: 10.1186/s13550-024-01110-9
doi:
Types de publication
Journal Article
Langues
eng
Pagination
52Informations de copyright
© 2024. The Author(s).
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