Dermal bioavailability of perfluoroalkyl substances using in vitro 3D human skin equivalent models.

3D-human skin equivalents Bioavailability Dermal absorption Episkin PFAS

Journal

Environment international
ISSN: 1873-6750
Titre abrégé: Environ Int
Pays: Netherlands
ID NLM: 7807270

Informations de publication

Date de publication:
23 May 2024
Historique:
received: 11 01 2024
revised: 03 05 2024
accepted: 21 05 2024
medline: 30 5 2024
pubmed: 30 5 2024
entrez: 29 5 2024
Statut: aheadofprint

Résumé

Perfluoroalkyl substances (PFAS) have been identified in various products that come in contact with human skin, ranging from school uniforms to personal care products. Despite this, knowledge on human dermal uptake of PFAS is lacking. Thus, the human dermal absorption of 17 PFAS was assessed, for the first time, using in vitro 3D-human skin equivalent models exposed to 500 ng/cm

Identifiants

pubmed: 38810496
pii: S0160-4120(24)00358-1
doi: 10.1016/j.envint.2024.108772
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

108772

Informations de copyright

Copyright © 2024. Published by Elsevier Ltd.

Déclaration de conflit d'intérêts

Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Auteurs

Oddný Ragnarsdóttir (O)

School of Geography, Earth & Environmental Sciences, University of Birmingham, Birmingham B15 2TT, UK. Electronic address: o.ragnarsdottir@bham.ac.uk.

Mohamed Abou-Elwafa Abdallah (M)

School of Geography, Earth & Environmental Sciences, University of Birmingham, Birmingham B15 2TT, UK.

Stuart Harrad (S)

School of Geography, Earth & Environmental Sciences, University of Birmingham, Birmingham B15 2TT, UK.

Classifications MeSH