Biologic Impact of Anterior Cruciate Ligament Injury and Reconstruction.

Humans Anterior Cruciate Ligament Reconstruction Anterior Cruciate Ligament Injuries / surgery Wound Healing / physiology Inflammation Quality of Life
ACL injury ACL reconstruction Graft healing Inflammation

Journal

Clinics in sports medicine
ISSN: 1556-228X
Titre abrégé: Clin Sports Med
Pays: United States
ID NLM: 8112473

Informations de publication

Date de publication:
Jul 2024
Historique:
medline: 30 5 2024
pubmed: 30 5 2024
entrez: 29 5 2024
Statut: ppublish

Résumé

Surgical intervention after anterior cruciate ligament (ACL) tears is typically required because of the limited healing capacity of the ACL. However, mechanical factors and the inflammatory response triggered by the injury and surgery can impact patient outcomes. This review explores key aspects of ACL injury and reconstruction biology, including the inflammatory response, limited spontaneous healing, secondary inflammation after reconstruction, and graft healing processes. Understanding these biologic mechanisms is crucial for developing new treatment strategies and enhancing patient well-being. By shedding light on these aspects, clinicians and researchers can work toward improving quality of life for individuals affected by ACL tears.

Identifiants

DOI: 10.1016/j.csm.2023.07.003 PMID: 38811124
pubmed: 38811124
pii: S0278-5919(23)00089-3
doi: 10.1016/j.csm.2023.07.003
pii:
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

501-512

Informations de copyright

Copyright © 2023 Elsevier Inc. All rights reserved.

Auteurs

Chilan B G Leite (CBG)

Department of Orthopaedic Surgery, Center for Cartilage Repair and Sports Medicine, Brigham and Women's Hospital, Harvard Medical School, 75 Francis Street, Boston, MA 02115, USA.

Richard Smith (R)

Department of Orthopaedic Surgery, Center for Cartilage Repair and Sports Medicine, Brigham and Women's Hospital, Harvard Medical School, 75 Francis Street, Boston, MA 02115, USA.

Ophelie Z Lavoie-Gagne (OZ)

Department of Orthopaedic Surgery, Center for Cartilage Repair and Sports Medicine, Brigham and Women's Hospital, Harvard Medical School, 75 Francis Street, Boston, MA 02115, USA.

Simon Görtz (S)

Department of Orthopaedic Surgery, Center for Cartilage Repair and Sports Medicine, Brigham and Women's Hospital, Harvard Medical School, 75 Francis Street, Boston, MA 02115, USA.

Christian Lattermann (C)

Department of Orthopaedic Surgery, Center for Cartilage Repair and Sports Medicine, Brigham and Women's Hospital, Harvard Medical School, 75 Francis Street, Boston, MA 02115, USA. Electronic address: clattermann@bwh.harvard.edu.

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Biologic Impact of Anterior Cruciate Ligament...
questionsmedicales.fr › Procédures de chirurgie opératoire › Procédures de chirurgie reconstructive › Arthroplastie › Reconstruction du ligament croisé antérieur › Biologic Impact of Anterior Cruciate Ligament...
questionsmedicales.fr › Plaies et blessures › Traumatismes de la jambe › Traumatismes du genou › Lésions du ligament croisé antérieur › Biologic Impact of Anterior Cruciate Ligament...
questionsmedicales.fr › Phénomènes biologiques › Régénération › Cicatrisation de plaie › Biologic Impact of Anterior Cruciate Ligament...
questionsmedicales.fr › États, signes et symptômes pathologiques › Processus pathologiques › Inflammation › Biologic Impact of Anterior Cruciate Ligament...
questionsmedicales.fr › Environnement et santé publique › Santé publique › Mesures épidémiologiques › Démographie › État de santé › Qualité de vie › Biologic Impact of Anterior Cruciate Ligament...