Effects of physical activity on infertility in reproductive females.
Infertility
Lifestyle
Physical activity
Recreation activity
Work activity
Journal
Reproductive biology and endocrinology : RB&E
ISSN: 1477-7827
Titre abrégé: Reprod Biol Endocrinol
Pays: England
ID NLM: 101153627
Informations de publication
Date de publication:
29 May 2024
29 May 2024
Historique:
received:
27
03
2024
accepted:
15
05
2024
medline:
30
5
2024
pubmed:
30
5
2024
entrez:
29
5
2024
Statut:
epublish
Résumé
To explore the relationship between different types of physical activity and female infertility. This study analyzed data from 2,796 female participants aged 18-44 years in the United States, obtained from the National Health and Nutrition Examination Survey (NHANES) database spanning the years 2013 to 2020. Multiple logistic regression analyses and generalized linear models were used to explore the relationship between different types of physical activity and infertility after adjusting for potential confounding factors. We found a non-linear relationship between recreational activities and infertility with an inflection point of 5.83 h/week (moderate intensity), while work activities and traffic-related activities did not. On the left side of the inflection point, there was no significant association between recreational activity time and infertility (OR = 0.93, 95% CI: 0.86 to 1.02, P = 0.1146), but on the right side of the inflection point, there was a positive association between recreational activity time and the risk of infertility (OR = 1.04, 95% CI: 1.02 to 1.06, P = 0.0008). The relationship between different types of physical activity and female infertility varies. We acknowledge the potential influence of confounding variables on this relationship. However, we have already adjusted for these potential variables in our analysis. Therefore, our findings suggest that appropriate recreational activity programs are essential for promoting reproductive health in women of reproductive age. Nevertheless, it is important to note that the observed association does not imply causality. Given the limitations of cross-sectional studies, further prospective cohort studies are needed to explore the causal relationship while accounting for additional confounding factors.
Identifiants
pubmed: 38811989
doi: 10.1186/s12958-024-01234-6
pii: 10.1186/s12958-024-01234-6
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
62Informations de copyright
© 2024. The Author(s).
Références
Vander Borght M, Wyns C. Fertility and infertility: definition and epidemiology. Clin Biochem. 2018;62:2–10.
doi: 10.1016/j.clinbiochem.2018.03.012
pubmed: 29555319
Hou C, Zhao X, Tian GG, Wu J. Stella regulates the development of female germline stem cells by modulating chromatin structure and DNA methylation. Int J Biol Sci. 2022;18:3006–18.
doi: 10.7150/ijbs.69240
pubmed: 35541912
pmcid: 9066111
Wang G, Liu X, Lei J. Cognitive behavioural therapy for women with infertility: a systematic review and meta-analysis. Clin Psychol Psychother. 2023;30:38–53.
doi: 10.1002/cpp.2792
pubmed: 36239578
Hutcherson NEC, Harris JB, Karaoui LR, Lakdawala L, Lodise NM, Stone RH, et al. Infertility management and pharmacotherapy: what every pharmacist should know. J Pharm Pract. 2021;34:635–47.
doi: 10.1177/0897190020930969
pubmed: 32588713
Stentz NC, Koelper N, Barnhart KT, Sammel MD, Senapati S. Infertility and mortality. Am J Obstet Gynecol. 2020;222:251.e1-251.e10.
doi: 10.1016/j.ajog.2019.09.007
pubmed: 31526792
Lundberg FE, Iliadou AN, Rodriguez-Wallberg K, Gemzell-Danielsson K, Johansson ALV. The risk of breast and gynecological cancer in women with a diagnosis of infertility: a nationwide population-based study. Eur J Epidemiol. 2019;34:499–507.
doi: 10.1007/s10654-018-0474-9
pubmed: 30623293
pmcid: 6456460
Nik Hazlina NH, Norhayati MN, Shaiful Bahari I, Nik Muhammad Arif NA. Worldwide prevalence, risk factors and psychological impact of infertility among women: a systematic review and meta-analysis. BMJ Open. 2022;12: e057132.
doi: 10.1136/bmjopen-2021-057132
pubmed: 35354629
pmcid: 8968640
Wu AK, Elliott P, Katz PP, Smith JF. Time costs of fertility care: the hidden hardship of building a family. Fertil Steril. 2013;99:2025–30.
doi: 10.1016/j.fertnstert.2013.01.145
pubmed: 23454007
pmcid: 3736984
Caspersen CJ, Powell KE, Christenson GM. Physical activity, exercise, and physical fitness: definitions and distinctions for health-related research. Public Health Rep. 1985;100:126–31.
pubmed: 3920711
pmcid: 1424733
Laakkonen EK, Kulmala J, Aukee P, Hakonen H, Kujala UM, Lowe DA, et al. Female reproductive factors are associated with objectively measured physical activity in middle-aged women. PLoS One. 2017;12: e0172054.
doi: 10.1371/journal.pone.0172054
pubmed: 28225786
pmcid: 5321412
Orio F, Muscogiuri G, Ascione A, Marciano F, Volpe A, La Sala G, et al. Effects of physical exercise on the female reproductive system. Minerva Endocrinol. 2013;38:305–19.
pubmed: 24126551
Florack EI, Zielhuis GA, Rolland R. The influence of occupational physical activity on the menstrual cycle and fecundability. Epidemiology. 1994;5:14–8.
doi: 10.1097/00001648-199401000-00004
pubmed: 8117776
ACOG committee opinion. 762: prepregnancy counseling. Obstet Gynecol. 2019;133(1):e78-89.
doi: 10.1097/AOG.0000000000003013
Gudmundsdottir SL, Flanders WD, Augestad LB. Physical activity and fertility in women: the North-Trøndelag Health Study. Hum Reprod. 2009;24:3196–204.
doi: 10.1093/humrep/dep337
pubmed: 19801570
Dhair A, Abed Y. The association of types, intensities and frequencies of physical activity with primary infertility among females in Gaza Strip, Palestine: a case-control study. PLoS ONE. 2020;15: e0241043.
doi: 10.1371/journal.pone.0241043
pubmed: 33095804
pmcid: 7584224
Tempest N, France-Ratcliffe M, Al-Lamee H, Oliver ER, Slaine EE, Drakeley AJ, et al. Habitual physical activity levels in women attending the one stop infertility clinic: a prospective cross-sectional observational study. Reprod Fertil. 2022;3:231–7.
doi: 10.1530/RAF-22-0067
pubmed: 36083716
pmcid: 9578060
Vitek WS, Sun F, Cardozo E, Hoeger KM, Hansen KR, Santoro N, et al. Moderate and increased physical activity is not detrimental to live birth rates among women with unexplained infertility and obesity. F S Rep. 2023;4:308–12.
pubmed: 37719091
pmcid: 10504528
Foucaut A-M, Faure C, Julia C, Czernichow S, Levy R, Dupont C, et al. Sedentary behavior, physical inactivity and body composition in relation to idiopathic infertility among men and women. PLoS ONE. 2019;14: e0210770.
doi: 10.1371/journal.pone.0210770
pubmed: 31017887
pmcid: 6481765
Läänelaid S, Ortega FB, Kunovac Kallak T, Joelsson L, Ruiz JR, Hreinsson J, et al. Physical and Sedentary Activities in Association with Reproductive outcomes among couples seeking infertility treatment: a prospective cohort study. Int J Environ Res Public Health. 2021;18: 2718.
doi: 10.3390/ijerph18052718
pubmed: 33800259
pmcid: 7967443
Ainsworth BE, Haskell WL, Whitt MC, Irwin ML, Swartz AM, Strath SJ, et al. Compendium of physical activities: an update of activity codes and MET intensities. Med Sci Sports Exerc. 2000;32:S498-504.
doi: 10.1097/00005768-200009001-00009
pubmed: 10993420
von Elm E, Altman DG, Egger M, Pocock SJ, Gøtzsche PC, Vandenbroucke JP, et al. The strengthening the reporting of Observational studies in Epidemiology (STROBE) Statement: guidelines for reporting observational studies. Int J Surg. 2014;12:1495–9.
doi: 10.1016/j.ijsu.2014.07.013
Jaddoe VWV, de Jonge LL, Hofman A, Franco OH, Steegers EAP, Gaillard R. First trimester fetal growth restriction and cardiovascular risk factors in school age children: population based cohort study. BMJ. 2014;348: g14.
doi: 10.1136/bmj.g14
pubmed: 24458585
pmcid: 3901421
Talmor A, Dunphy B. Female obesity and infertility. Best Pract Res Clin Obstet Gynaecol. 2015;29:498–506.
doi: 10.1016/j.bpobgyn.2014.10.014
pubmed: 25619586
He S, Wan L. Associations between smoking status and infertility: a cross-sectional analysis among USA women aged 18–45 years. Front Endocrinol (Lausanne). 2023;14: 1140739.
doi: 10.3389/fendo.2023.1140739
pubmed: 37181041
Tolstrup JS, Kjær SK, Holst C, Sharif H, Munk C, Osler M, et al. Alcohol use as predictor for infertility in a representative population of Danish women. Acta Obstet Gynecol Scand. 2003;82:744–9.
doi: 10.1034/j.1600-0412.2003.00164.x
pubmed: 12848646
Holtermann A, Schnohr P, Nordestgaard BG, Marott JL. The physical activity paradox in cardiovascular disease and all-cause mortality: the contemporary Copenhagen General Population Study with 104 046 adults. Eur Heart J. 2021;42:1499–511.
doi: 10.1093/eurheartj/ehab087
pubmed: 33831954
pmcid: 8046503
Huang Y, Xu P, Fu X, Ren Z, Cheng J, Lin Z, et al. The effect of triglycerides in the associations between physical activity, sedentary behavior and depression: an interaction and mediation analysis. J Affect Disord. 2021;295:1377–85.
doi: 10.1016/j.jad.2021.09.005
pubmed: 34565593
White RL, Babic MJ, Parker PD, Lubans DR, Astell-Burt T, Lonsdale C. Domain-specific physical activity and mental health: a meta-analysis. Am J Prev Med. 2017;52:653–66.
doi: 10.1016/j.amepre.2016.12.008
pubmed: 28153647
Ryterska K, Kordek A, Załęska P. Has menstruation disappeared? Functional hypothalamic amenorrhea-what is this story about? Nutrients. 2021;13: 2827.
doi: 10.3390/nu13082827
pubmed: 34444987
pmcid: 8401547
Evenson KR, Hesketh KR. Studying the Complex relationships between physical activity and infertility. Am J Lifestyle Med. 2016;10:232–4.
doi: 10.1177/1559827616641379
pubmed: 27895545
pmcid: 5123562