Ictal activity is sustained by the estrogen receptor β during the estrous cycle.

4-Aminopyridine Catamenial epilepsy Chirps Estrogen receptor β-mediated signaling Estrous cycles Interneurons Seizures

Journal

Current research in neurobiology
ISSN: 2665-945X
Titre abrégé: Curr Res Neurobiol
Pays: Netherlands
ID NLM: 101778135

Informations de publication

Date de publication:
2024
Historique:
received: 13 02 2024
revised: 16 04 2024
accepted: 05 05 2024
medline: 30 5 2024
pubmed: 30 5 2024
entrez: 30 5 2024
Statut: epublish

Résumé

Catamenial epilepsy, defined as a periodicity of seizure exacerbation during the menstrual cycle, affects up to 70 % of epileptic women. Seizures in these patients are often non-responsive to medication; however, our understanding of the relation between menstrual cycle and seizure generation (i.e. ictogenesis) remains limited. We employed here field potential recordings in the

Identifiants

pubmed: 38812499
doi: 10.1016/j.crneur.2024.100131
pii: S2665-945X(24)00008-1
pmc: PMC11134549
doi:

Types de publication

Journal Article

Langues

eng

Pagination

100131

Informations de copyright

© 2024 The Authors.

Déclaration de conflit d'intérêts

The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Auteurs

Fei Ran Li (FR)

Montreal Neurological Institute-Hospital and Departments of Neurology & Neurosurgery, Montréal, Québec, H3A 2B4, Canada.
Physiology, McGill University, 3801 University Street, Montréal, Québec H3A 2B4, Canada.

Maxime Lévesque (M)

Montreal Neurological Institute-Hospital and Departments of Neurology & Neurosurgery, Montréal, Québec, H3A 2B4, Canada.

Siyan Wang (S)

Montreal Neurological Institute-Hospital and Departments of Neurology & Neurosurgery, Montréal, Québec, H3A 2B4, Canada.

Maria-Isabel Carreño-Muñoz (MI)

Neurosciences Department, Université de Montréal, Montréal, Québec H3T 1N8, Canada.
CHU Sainte-Justine Research Center, Montréal, Québec H3T 1C5, Canada.

Graziella Di Cristo (G)

Neurosciences Department, Université de Montréal, Montréal, Québec H3T 1N8, Canada.
CHU Sainte-Justine Research Center, Montréal, Québec H3T 1C5, Canada.

Massimo Avoli (M)

Montreal Neurological Institute-Hospital and Departments of Neurology & Neurosurgery, Montréal, Québec, H3A 2B4, Canada.
Physiology, McGill University, 3801 University Street, Montréal, Québec H3A 2B4, Canada.

Classifications MeSH