Prospective study of the effects of isotretinoin and vitamin D levels on severe acne vulgaris.
Acne vulgaris
isotretinoin
vitamin D
Journal
Turkish journal of medical sciences
ISSN: 1303-6165
Titre abrégé: Turk J Med Sci
Pays: Turkey
ID NLM: 9441758
Informations de publication
Date de publication:
2023
2023
Historique:
received:
29
05
2023
revised:
12
12
2023
accepted:
20
09
2023
medline:
30
5
2024
pubmed:
30
5
2024
entrez:
30
5
2024
Statut:
epublish
Résumé
Acne vulgaris (AV) is a common inflammatory skin condition associated with psychological and social distress. Its pathogenesis involves factors such as sebaceous hypersecretion and One hundred patients with severe AV were enrolled, each receiving 0.75 mg/kg IOS treatment daily for 4 months. Serum 25 OH vitamin D levels were measured before, during, and after treatment. This study found a significant increase in serum 25 OH vitamin D levels among patients with severe AV following IOS treatment (p < 0.001). This study suggests that AV may negatively impact vitamin D synthesis, but IOS treatment appears to raise vitamin D serum levels in individuals with severe AV. Further research is needed to confirm the potential relationship between AV and vitamin D levels.
Sections du résumé
Background/aim
UNASSIGNED
Acne vulgaris (AV) is a common inflammatory skin condition associated with psychological and social distress. Its pathogenesis involves factors such as sebaceous hypersecretion and
Materials and methods
UNASSIGNED
One hundred patients with severe AV were enrolled, each receiving 0.75 mg/kg IOS treatment daily for 4 months. Serum 25 OH vitamin D levels were measured before, during, and after treatment.
Results
UNASSIGNED
This study found a significant increase in serum 25 OH vitamin D levels among patients with severe AV following IOS treatment (p < 0.001).
Conclusion
UNASSIGNED
This study suggests that AV may negatively impact vitamin D synthesis, but IOS treatment appears to raise vitamin D serum levels in individuals with severe AV. Further research is needed to confirm the potential relationship between AV and vitamin D levels.
Identifiants
pubmed: 38813517
doi: 10.55730/1300-0144.5742
pii: turkjmedsci-53-6-1732
pmc: PMC10760531
doi:
Substances chimiques
Isotretinoin
EH28UP18IF
Vitamin D
1406-16-2
Dermatologic Agents
0
25-hydroxyvitamin D
A288AR3C9H
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
1732-1737Informations de copyright
© TÜBİTAK.
Déclaration de conflit d'intérêts
Conflict of interest: The authors declare that there is no conflict of interest.