Patient-derived induced pluripotent stem cells with a

Cell junction Cellular differentiation Extracellular vesicle Human induced pluripotent stem cells Proteomics Transcriptomics

Journal

World journal of stem cells
ISSN: 1948-0210
Titre abrégé: World J Stem Cells
Pays: United States
ID NLM: 101535826

Informations de publication

Date de publication:
26 May 2024
Historique:
received: 13 12 2023
revised: 29 01 2024
accepted: 01 04 2024
medline: 31 5 2024
pubmed: 31 5 2024
entrez: 31 5 2024
Statut: ppublish

Résumé

Human induced pluripotent stem cell (hiPSC) technology is a valuable tool for generating patient-specific stem cells, facilitating disease modeling, and investigating disease mechanisms. However, iPSCs carrying specific mutations may limit their clinical applications due to certain inherent characteristics. To investigate the impact of We employed a non-integrating reprogramming technique to generate peripheral blood-derived hiPSCs with and hiPSCs without a The generated hiPSCs, both with and without a HiPSCs with a

Sections du résumé

BACKGROUND BACKGROUND
Human induced pluripotent stem cell (hiPSC) technology is a valuable tool for generating patient-specific stem cells, facilitating disease modeling, and investigating disease mechanisms. However, iPSCs carrying specific mutations may limit their clinical applications due to certain inherent characteristics.
AIM OBJECTIVE
To investigate the impact of
METHODS METHODS
We employed a non-integrating reprogramming technique to generate peripheral blood-derived hiPSCs with and hiPSCs without a
RESULTS RESULTS
The generated hiPSCs, both with and without a
CONCLUSION CONCLUSIONS
HiPSCs with a

Identifiants

DOI: 10.4252/wjsc.v16.i5.512 PMID: 38817331 PMC: PMC11135251
pubmed: 38817331
doi: 10.4252/wjsc.v16.i5.512
pmc: PMC11135251
doi:

Types de publication

Journal Article

Langues

eng

Pagination

512-524

Informations de copyright

©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.

Déclaration de conflit d'intérêts

Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.

Auteurs

Hang Zhang (H)

Beijing Institute of Ophthalmology, Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing 100730, China.

Ling-Zi Wu (LZ)

Beijing Institute of Ophthalmology, Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing 100730, China.

Zhen-Yu Liu (ZY)

Beijing Institute of Ophthalmology, Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing 100730, China.

Zi-Bing Jin (ZB)

Beijing Institute of Ophthalmology, Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing 100730, China. jinzb502@ccmu.edu.cn.

Classifications MeSH