Acellular Fish Skin Grafts for Treatment of Periocular Skin Defects.


Journal

Ophthalmic plastic and reconstructive surgery
ISSN: 1537-2677
Titre abrégé: Ophthalmic Plast Reconstr Surg
Pays: United States
ID NLM: 8508431

Informations de publication

Date de publication:
31 May 2024
Historique:
medline: 31 5 2024
pubmed: 31 5 2024
entrez: 31 5 2024
Statut: aheadofprint

Résumé

To describe the outcomes of acellular fish skin grafts for repair of periocular anterior lamella skin defects after Mohs surgery for skin cancers. Following the institutional review board approval, we conducted a retrospective chart review of patients treated with acellular fish skin grafts between January 2022 and December 2023. Indication was to repair defects after Mohs excision of basal cell carcinoma and squamous cell carcinoma. Demographics, smoking and diabetes status, diagnosis, defect location, graft size, and complications were evaluated. Outcomes were analyzed using the scar cosmesis assessment and rating scale. Six patients (3 females and 3 males) with a mean age of 60.8 (range 44-80) had Mohs surgery for basal cell carcinoma (4) and squamous cell carcinoma (2). Location of defects included eyebrow (3 cases), lateral nasal wall (1 case), lower eyelid (1 case), and medial lower eyelid/nasal wall (1 case). Defect size ranged from 8 × 10 mm to 30 × 40 mm. Two patients had more than 1 application of xenograft. One patient developed a mild cicatricial ectropion. No other postoperative complications were seen, and all had good wound healing and cosmetically acceptable results. In this pilot study, acellular fish skin xenografts are shown to be promising skin graft substitutes in patients with Mohs defects and decrease the need for autologous skin harvesting or allogenic skin donation.

Identifiants

pubmed: 38819161
doi: 10.1097/IOP.0000000000002699
pii: 00002341-990000000-00418
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Informations de copyright

Copyright © 2024 The Author(s). Published by Wolters Kluwer Health, Inc. on behalf of he American Society of Ophthalmic Plastic and Reconstructive Surgery, Inc.

Déclaration de conflit d'intérêts

The authors have no financial or conflicts of interest to disclose.

Références

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Auteurs

Diane Wang (D)

Department of Ophthalmology and Visual Sciences, West Virginia University, Morgantown, West Virginia.

Janice Maliakkal (J)

Department of Ophthalmology, George Washington University, Washington, District of Columbia.

Omar Sadat (O)

Department of Ophthalmology and Visual Sciences, West Virginia University, Morgantown, West Virginia.

Vlad Codrea (V)

Department of Dermatology, West Virginia University, Morgantown, West Virginia.

John Nguyen (J)

Department of Ophthalmology and Visual Sciences, West Virginia University, Morgantown, West Virginia.
Department of Otolaryngology, Head and Neck Surgery, West Virginia University, Morgantown, West Virginia, U.S.A.

Classifications MeSH