Continuous Electroencephalogram (cEEG) Findings and Neurodevelopmental Outcomes in Neonates with Congenital Heart Disease (CHD) at 12-24 Months of Age.

Congenital Heart Disease (CHD) Electroencephalogram (EEG) Neurodevelopmental outcomes

Journal

Journal of autism and developmental disorders
ISSN: 1573-3432
Titre abrégé: J Autism Dev Disord
Pays: United States
ID NLM: 7904301

Informations de publication

Date de publication:
31 May 2024
Historique:
accepted: 21 05 2024
medline: 31 5 2024
pubmed: 31 5 2024
entrez: 31 5 2024
Statut: aheadofprint

Résumé

This study aims to assess the role of continuous EEG (cEEG) background patterns and duration of cross-clamp time and cardiopulmonary bypass (CPB) in children with congenital heart disease (CHD) undergoing cardiac surgery and its correlation with abnormal neurodevelopmental outcomes at 12-24 months on Bayley Scales of Infant and Toddler Development (BSID-III). This retrospective cohort study included infants with CHD and cEEG monitoring, who underwent surgery by 44 weeks gestational age. 34 patients were included, who were operated at median age - 7 days. Longer duration of cross- camp time was associated with poor language composite scores (LCS) (p value = 0.036). A significant association existed between severity of encephalopathy in 24-hour post-operative period and poor LCS (p value = 0.026). Majority of neonates with CHD have below average cognitive, language and motor composite scores on BSID-III. Longer duration of cross-clamp time and severity of encephalopathy during 24-hour post-operative EEG monitoring are associated with poor LCS.

Identifiants

pubmed: 38819704
doi: 10.1007/s10803-024-06418-y
pii: 10.1007/s10803-024-06418-y
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Informations de copyright

© 2024. The Author(s).

Références

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Auteurs

Swetha Padiyar (S)

Department of Neonatology, Cleveland Clinic Children's Hospital, 9500 Euclid Ave, M-31, Cleveland, OH, 44195, USA. swetha.padiyar@gmail.com.

Neil Friedman (N)

Department of Neurology, Barrow Neurological Institute at Phoenix Children's Hospital, Phoenix, AZ, USA.

Elia Pestana-Knight (E)

Epilepsy Center, Cleveland Clinic, Cleveland, OH, USA.

Linda Franic (L)

Epilepsy Center, Cleveland Clinic, Cleveland, OH, USA.

Sarah Worley (S)

Department of Quantitative Health Sciences, Cleveland Clinic, Cleveland, OH, USA.

Hany Aly (H)

Department of Neonatology, Cleveland Clinic Children's Hospital, 9500 Euclid Ave, M-31, Cleveland, OH, 44195, USA.

Classifications MeSH