Clinical Features and Predictors of Treatment Outcome in Patients with Ocular Tuberculosis from the Netherlands and Indonesia: The OculaR TB in Low versus High Endemic Countries (ORTEC) Study.

Clinical feature ocular tuberculosis outcome predictor treatment

Journal

Ocular immunology and inflammation
ISSN: 1744-5078
Titre abrégé: Ocul Immunol Inflamm
Pays: England
ID NLM: 9312169

Informations de publication

Date de publication:
31 May 2024
Historique:
medline: 31 5 2024
pubmed: 31 5 2024
entrez: 31 5 2024
Statut: aheadofprint

Résumé

To describe and compare clinical features, treatment approaches, and treatment outcomes of ocular tuberculosis (OTB) patients in the Netherlands, a low tuberculosis (TB)-endemic country, and Indonesia, a high TB-endemic country. We also aimed to identify predictors of treatment outcomes. A medical chart review of 339 OTB patients ( Indonesian OTB patients displayed a higher prevalence of chest radiograph findings indicative of TB infection ( Despite a more severe initial clinical presentation in the Indonesian cohort, the overall treatment outcomes of OTB was comparable in both cohorts. Three baseline clinical features were identified as predictors of treatment outcomes.

Identifiants

pubmed: 38820475
doi: 10.1080/09273948.2024.2359614
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

1-12

Auteurs

Ikhwanuliman Putera (I)

Department of Ophthalmology, Erasmus University Medical Center, Rotterdam, The Netherlands.
Department of Internal Medicine Section Allergy and Clinical Immunology, Erasmus University Medical Center, Rotterdam, The Netherlands.
Department of Immunology, Clinical and Laboratory Medical Immunology, Erasmus University Medical Center, Rotterdam, The Netherlands.
Department of Ophthalmology, Faculty of Medicine, Universitas Indonesia - Cipto Mangunkusumo Hospital, Jakarta, Indonesia.

Josianne C E M Ten Berge (JCEM)

Department of Ophthalmology, Erasmus University Medical Center, Rotterdam, The Netherlands.

Alberta A H J Thiadens (AAHJ)

Department of Ophthalmology, Erasmus University Medical Center, Rotterdam, The Netherlands.

Willem A Dik (WA)

Department of Immunology, Clinical and Laboratory Medical Immunology, Erasmus University Medical Center, Rotterdam, The Netherlands.

Rupesh Agrawal (R)

Lee Kong Chian School of Medicine, Nanyang Technological University of Singapore, Singapore.
National Healthcare Group Eye Institute, Tan Tock Seng Hospital, Singapore, Singapore.
Duke NUS Medical School, Singapore, Singapore.
Ocular Infections and Antimicrobial Group, Singapore Eye Research Institute, Singapore, Singapore.
National Institute for Health Research Biomedical Research Centre, Moorfields Eye Hospital, London, UK.

P Martin van Hagen (PM)

Department of Internal Medicine Section Allergy and Clinical Immunology, Erasmus University Medical Center, Rotterdam, The Netherlands.
Department of Immunology, Clinical and Laboratory Medical Immunology, Erasmus University Medical Center, Rotterdam, The Netherlands.

Rina La Distia Nora (R)

Department of Immunology, Clinical and Laboratory Medical Immunology, Erasmus University Medical Center, Rotterdam, The Netherlands.
Department of Ophthalmology, Faculty of Medicine, Universitas Indonesia - Cipto Mangunkusumo Hospital, Jakarta, Indonesia.

Saskia M Rombach (SM)

Department of Internal Medicine Section Allergy and Clinical Immunology, Erasmus University Medical Center, Rotterdam, The Netherlands.

Classifications MeSH