Thermal Ablation for Small Renal Masses: Identifying Anthropometric Factors for Predicting Perioperative and Oncological Outcomes.

Anthropometric parameters Kidney cancer Percutaneous thermal ablation Perioperative outcomes TRIFECTA

Journal

Clinical genitourinary cancer
ISSN: 1938-0682
Titre abrégé: Clin Genitourin Cancer
Pays: United States
ID NLM: 101260955

Informations de publication

Date de publication:
30 Apr 2024
Historique:
received: 12 03 2024
revised: 23 04 2024
accepted: 27 04 2024
medline: 1 6 2024
pubmed: 1 6 2024
entrez: 31 5 2024
Statut: aheadofprint

Résumé

To test for specific anthropometric parameters to predict perioperative outcomes after thermal ablation (TA) for renal cell carcinoma (RCC). Retrospective single center (2008-2022) analysis of 538 T1a-b RCC patients treated with TA. We tested for specific anthropometric parameters, namely skin to tumor distance (STTD), perirenal fat thickness (PFT), median psoas muscle axial area (PMAA) and median paravertebral muscle axial area (PVMAA), to predict TRIFECTA achievement: (1) absence of CLAVIEN-DINDO≥ 3 complications; (2) complete ablation; (3) absence of ≥ 30% decrease in eGFR. Univariable (ULRM) and multivariable logistic regression models (MLRM) were used for testing TRIFECTA achievement. Overall, 103 patients (19%) did not achieve TRIFECTA. Of all anthropometric factors, only lower PMAA was associated with no TRIFECTA achievement (10 vs. 11 cm None of the tested anthropometric parameters predicted TRIFECTA achievement. However, when the 3 specific TRIFECTA items were tested, STTD and PFT were associated with, respectively, incomplete ablation and CLAVIEN-DINDO ≥ 3 complications.

Identifiants

pubmed: 38820997
pii: S1558-7673(24)00080-6
doi: 10.1016/j.clgc.2024.102109
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

102109

Informations de copyright

Copyright © 2024 Elsevier Inc. All rights reserved.

Déclaration de conflit d'intérêts

Disclosure None.

Auteurs

Gennaro Musi (G)

Department of Urology, European Institute of Oncology (IEO), IRCCS, Milan, Italy; Department of Oncology and Hemato-Oncology, Università degli Studi di Milano, Milan, Italy.

Chiara Vaccaro (C)

Department of Urology, European Institute of Oncology (IEO), IRCCS, Milan, Italy.

Stefano Luzzago (S)

Department of Urology, European Institute of Oncology (IEO), IRCCS, Milan, Italy; Department of Oncology and Hemato-Oncology, Università degli Studi di Milano, Milan, Italy.

Giovanni Mauri (G)

Department of Interventional Radiology, European Institute of Oncology (IEO), IRCCS, Milan, Italy.

Mattia Luca Piccinelli (ML)

Department of Urology, European Institute of Oncology (IEO), IRCCS, Milan, Italy.

Daniele Maiettini (D)

Department of Interventional Radiology, European Institute of Oncology (IEO), IRCCS, Milan, Italy.

Marco Tozzi (M)

Department of Urology, European Institute of Oncology (IEO), IRCCS, Milan, Italy.

Gianluca Varano (G)

Department of Interventional Radiology, European Institute of Oncology (IEO), IRCCS, Milan, Italy.

Ettore Di Trapani (E)

Department of Urology, European Institute of Oncology (IEO), IRCCS, Milan, Italy.

Paolo Della Vigna (P)

Department of Interventional Radiology, European Institute of Oncology (IEO), IRCCS, Milan, Italy.

Giovanni Cordima (G)

Department of Urology, European Institute of Oncology (IEO), IRCCS, Milan, Italy.

Matteo Ferro (M)

Department of Urology, European Institute of Oncology (IEO), IRCCS, Milan, Italy.

Guido Bonomo (G)

Department of Interventional Radiology, European Institute of Oncology (IEO), IRCCS, Milan, Italy.

Ottavio de Cobelli (O)

Department of Urology, European Institute of Oncology (IEO), IRCCS, Milan, Italy; Department of Oncology and Hemato-Oncology, Università degli Studi di Milano, Milan, Italy.

Francesco A Mistretta (FA)

Department of Urology, European Institute of Oncology (IEO), IRCCS, Milan, Italy; Department of Oncology and Hemato-Oncology, Università degli Studi di Milano, Milan, Italy.

Franco Orsi (F)

Department of Interventional Radiology, European Institute of Oncology (IEO), IRCCS, Milan, Italy.

Classifications MeSH