Design of osteosynthesis plate for detecting bone union using wire natural frequency.
Journal
Scientific reports
ISSN: 2045-2322
Titre abrégé: Sci Rep
Pays: England
ID NLM: 101563288
Informations de publication
Date de publication:
31 May 2024
31 May 2024
Historique:
received:
15
05
2023
accepted:
29
05
2024
medline:
1
6
2024
pubmed:
1
6
2024
entrez:
31
5
2024
Statut:
epublish
Résumé
We have developed a novel osteosynthesis plate with bone union detection using a wire's natural frequency (BUDWF) to provide the quantitative result of bone union detection. The concept for detecting bone union is measuring the rate of frequency change. The frequency is measured from sound generated from the wire attached to a modified plate. The plate is modified from a Syncera ADLER B0409.10 and attached with 0.3 mm diameter 316L stainless steel wire. The sound generation mechanism was created by PEEK and installed on the plate to generate the sound. The preliminary experiments were conducted on a Sawbones tibia composite mimic. We used the cut Sawbones to create fracture samples with a 0, 0.5, 1-, 2-, and 5-mm gap representing the fractured bone with different gap sizes and prepared uncut Sawbones as a union sample. These samples were tested five times, and the sound was recorded from a condenser microphone and analyzed. We found that the BUDWF can differentiate samples with a fracture gap above 2 mm from the union sample, as the differences in the rates of frequency change between samples with a fracture gap above 2 mm and union samples were statistically significant. However, there was a limitation that the BUDWF plate was still unable to differentiate the 0 mm fracture gap and the union sample in this study.
Identifiants
pubmed: 38822126
doi: 10.1038/s41598-024-63530-w
pii: 10.1038/s41598-024-63530-w
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
12569Informations de copyright
© 2024. The Author(s).
Références
Pryde, J. A. & Iwasaki, D. H. in Physical Rehabilitation (eds Michelle H. Cameron & Linda G. Monroe) 194–218 (W.B. Saunders, 2007).
Morshed, S. Current options for determining fracture union. Adv. Med. 2014, 1–12. https://doi.org/10.1155/2014/708574 (2014).
doi: 10.1155/2014/708574
Singaram, S. & Naidoo, M. The physical, psychological and social impact of long bone fractures on adults: A review. Afr. J. Prim. Health Care Family Med. 11, 1–9. https://doi.org/10.4102/phcfm.v11i1.1908 (2019).
doi: 10.4102/phcfm.v11i1.1908
Haagsma, J. A. et al. The global burden of injury: Incidence, mortality, disability-adjusted life years and time trends from the global burden of disease study 2013. Inj. Prev. 22, 3–18. https://doi.org/10.1136/injuryprev-2015-041616 (2016).
doi: 10.1136/injuryprev-2015-041616
pubmed: 26635210
Einhorn, T. A. Enhancement of fracture-healing. JBJS 77, 940–956 (1995).
doi: 10.2106/00004623-199506000-00016
Hak, D. J. et al. Delayed union and nonunions: epidemiology, clinical issues, and financial aspects. Injury 45(Suppl 2), S3-7. https://doi.org/10.1016/j.injury.2014.04.002 (2014).
doi: 10.1016/j.injury.2014.04.002
pubmed: 24857025
Pinto, A. et al. Traumatic fractures in adults: Missed diagnosis on plain radiographs in the emergency department. Acta Biomed. 89, 111–123. https://doi.org/10.23750/abm.v89i1-S.7015 (2018).
doi: 10.23750/abm.v89i1-S.7015
pubmed: 29350641
pmcid: 6179080
Whelan, D. B. et al. Development of the radiographic union score for tibial fractures for the assessment of tibial fracture healing after intramedullary fixation. J. Trauma Acute Care Surg. 68, 629–632 (2010).
doi: 10.1097/TA.0b013e3181a7c16d
Bhandari, M. et al. Radiographic union score for hip substantially improves agreement between surgeons and radiologists. BMC Musculoskelet. Dis. 14, 70. https://doi.org/10.1186/1471-2474-14-70 (2013).
doi: 10.1186/1471-2474-14-70
Blokhuis, T. J. et al. The reliability of plain radiography in experimental fracture healing. Skelet. Radiol. 30, 151–156. https://doi.org/10.1007/s002560000317 (2001).
doi: 10.1007/s002560000317
Ledet, E. H., Liddle, B., Kradinova, K. & Harper, S. Smart implants in orthopedic surgery, improving patient outcomes: A review. Innov. Entrep. Health 5, 41–51. https://doi.org/10.2147/ieh.s133518 (2018).
doi: 10.2147/ieh.s133518
pubmed: 30246037
pmcid: 6145822
Richardson, J. B., Cunningham, J. L., Goodship, A. E., O’Connor, B. T. & Kenwright, J. Measuring stiffness can define healing of tibial fractures. J. Bone Joint Surg. Br. Vol. 76-B(3), 389–394. https://doi.org/10.1302/0301-620X.76B3.8175839 (1994).
doi: 10.1302/0301-620X.76B3.8175839
Richardson, J. B., Kenwright, J. & Cunningham, J. L. Fracture stiffness measurement in the assessment and management of tibial fractures. Clin. Biomech. 7, 75–79. https://doi.org/10.1016/0268-0033(92)90018-Y (1992).
doi: 10.1016/0268-0033(92)90018-Y
Kienast, B. et al. An electronically instrumented internal fixator for the assessment of bone healing. Bone Joint Res. 5, 191–197. https://doi.org/10.1302/2046-3758.55.2000611 (2016).
doi: 10.1302/2046-3758.55.2000611
pubmed: 27226357
pmcid: 4921051
Seide, K. et al. Telemetric assessment of bone healing with an instrumented internal fixator. J. Bone Joint Surg. Br. 94B, 398–404. https://doi.org/10.1302/0301-620x.94b3.27550 (2012).
doi: 10.1302/0301-620x.94b3.27550
McGilvray, K. C. et al. Implantable microelectromechanical sensors for diagnostic monitoring and post-surgical prediction of bone fracture healing. J. Orthop. Res. 33, 1439–1446. https://doi.org/10.1002/jor.22918 (2015).
doi: 10.1002/jor.22918
pubmed: 26174472
Bhavsar, M. B., Moll, J. & Barker, J. H. Bone fracture sensing using ultrasound pitch-catch measurements: A proof-of-principle study. Ultrasound Med. Biol. 46, 855–860. https://doi.org/10.1016/j.ultrasmedbio.2019.11.006 (2020).
doi: 10.1016/j.ultrasmedbio.2019.11.006
pubmed: 31806498
Alizad, A., Walch, M., Greenleaf, J. F. & Fatemi, M. Vibrational characteristics of bone fracture and fracture repair: Application to excised rat femur. J. Biomech. Eng. 128, 300–308. https://doi.org/10.1115/1.2187037 (2006).
doi: 10.1115/1.2187037
pubmed: 16706579
Umbrecht, F. et al. Wireless implantable passive strain sensor: Design, fabrication and characterization. J. Micromech. Microeng. 20, 085005. https://doi.org/10.1088/0960-1317/20/8/085005 (2010).
doi: 10.1088/0960-1317/20/8/085005
Rajamanthrilage, A. et al. Measuring orthopedic plate strain to track bone healing using a fluidic sensor read via plain radiography. IEEE Trans. Biomed. Eng. 69, 278–285. https://doi.org/10.1109/tbme.2021.3092291 (2022).
doi: 10.1109/tbme.2021.3092291
pubmed: 34181532
Cohen, H. F. Quantifying music: The science of music at the first stage of scientific revolution Vol. 308 (Springer, 2013).
Grimes, D. R. String theory–the physics of string-bending and other electric guitar techniques. PLoS One 9, e102088. https://doi.org/10.1371/journal.pone.0102088 (2014).
doi: 10.1371/journal.pone.0102088
pubmed: 25054880
pmcid: 4108333
Paul Peter Urone, R. H. Physics. 433 (OpenStax., 2020).
Akinmokun, O. & Ibeabuchi, N. Anthropometric study of adult tibia bone for pre-operative determination of length of intramedullary nail. East Afr. Med. J. 14, 14–22 (2020).
Katchy, A., Agu, A., Ikele, I., Esom, E. & Johnson, N. The morphology of proximal tibia geometry amongst the Igbos of South East Nigeria and its implication in total knee replacement. Niger. J. Clin. Pract. 22, 1423. https://doi.org/10.4103/njcp.njcp_93_19 (2019).
doi: 10.4103/njcp.njcp_93_19
pubmed: 31607734
Cristofolini, L. & Viceconti, M. Mechanical validation of whole bone composite tibia models. J. Biomech. 33, 279–288. https://doi.org/10.1016/S0021-9290(99)00186-4 (2000).
doi: 10.1016/S0021-9290(99)00186-4
pubmed: 10673111
Kim, T., See, C. W., Li, X. & Zhu, D. Orthopedic implants and devices for bone fractures and defects: Past, present and perspective. Eng. Regen. 1, 6–18. https://doi.org/10.1016/j.engreg.2020.05.003 (2020).
doi: 10.1016/j.engreg.2020.05.003
Kumar, S., Ng, R. & Lee, H. Experimental investigations of acoustic curtains for hospital environment noise mitigations. (2020).
Loupa, G., Katikaridis, A., Karali, D. & Rapsomanikis, S. Mapping the noise in a Greek general hospital. Sci. Total Environ. 646, 923–929. https://doi.org/10.1016/j.scitotenv.2018.07.315 (2019).
doi: 10.1016/j.scitotenv.2018.07.315
pubmed: 30067962
Aronson, J. K., Heneghan, C. & Ferner, R. E. Medical devices: Definition, classification, and regulatory implications. Drug Saf. 43, 83–93. https://doi.org/10.1007/s40264-019-00878-3 (2020).
doi: 10.1007/s40264-019-00878-3
pubmed: 31845212
Peter, L., Hajek, L., Maresova, P., Augustynek, M. & Penhaker, M. Medical devices: Regulation, risk classification, and open innovation. J. Open Innov. Technol. Market Complex. 6, 42. https://doi.org/10.3390/joitmc6020042 (2020).
doi: 10.3390/joitmc6020042