A cell type-specific approach to elucidate the role of miR-96 in inner ear hair cells.

Mutations in microRNA-96 (miR-96), a microRNA expressed within the hair cells (HCs) of the inner ear, result in progressive hearing loss in both mouse models and humans. In this study, we present the first HC-specific RNA-sequencing (RNA-seq) dataset from newborn Bulk RNA-seq was performed on HCs of newborn We identify 215 upregulated and 428 downregulated genes in the HCs of the Our data further support a role for miR-96 in HC development, possibly as a repressor of supporting cell transcriptional programs in HCs. The HC-specific

Déclaration de conflit d'intérêts

Conflict of interest The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.