Evaluation of antioxidant and antihyperglycemic effects
Antihyperglycemic
Antioxidant
Diabetes mellitus
Dovyalis abyssinica
Journal
Metabolism open
ISSN: 2589-9368
Titre abrégé: Metabol Open
Pays: England
ID NLM: 101767753
Informations de publication
Date de publication:
Jun 2024
Jun 2024
Historique:
received:
27
04
2024
revised:
10
05
2024
accepted:
18
05
2024
medline:
3
6
2024
pubmed:
3
6
2024
entrez:
3
6
2024
Statut:
epublish
Résumé
The leaves of To Evaluate the Antihyperglycemic, and Antioxidant Effects of Dovyalis Abyssinica Leaves Extract in Streptozotocin-Induced Diabetic Mice. Male Swiss albino mice were induced into diabetes using 100 mg/kg of streptozotocin. Mice were allocated randomly into six groups, six mice per group. The body weight and FBG measurements were done on days 0, 7th, 14th and 21st of treatment. Additionally, in vitro Antioxidant Activity of the Extract was determined using a DPPH assay. The data were entered into Epi-Data version 4.6, exported to SPSS version 26.0, and analysed by using a one-way ANOVA followed by a Tukey post hoc test, and P < 0.05 was considered statistically significant. Dovyalis Abyssinica leaves crude extract showed significant (P < 0.05-P< 0.001) blood-glucose-lowering activity. Moreover, the crude extract of The present findings revealed that
Sections du résumé
Background
UNASSIGNED
The leaves of
Methods
UNASSIGNED
To Evaluate the Antihyperglycemic, and Antioxidant Effects of Dovyalis Abyssinica Leaves Extract in Streptozotocin-Induced Diabetic Mice. Male Swiss albino mice were induced into diabetes using 100 mg/kg of streptozotocin. Mice were allocated randomly into six groups, six mice per group. The body weight and FBG measurements were done on days 0, 7th, 14th and 21st of treatment. Additionally, in vitro Antioxidant Activity of the Extract was determined using a DPPH assay. The data were entered into Epi-Data version 4.6, exported to SPSS version 26.0, and analysed by using a one-way ANOVA followed by a Tukey post hoc test, and P < 0.05 was considered statistically significant.
Results
UNASSIGNED
Dovyalis Abyssinica leaves crude extract showed significant (P < 0.05-P< 0.001) blood-glucose-lowering activity. Moreover, the crude extract of
Conclusion
UNASSIGNED
The present findings revealed that
Identifiants
pubmed: 38828006
doi: 10.1016/j.metop.2024.100286
pii: S2589-9368(24)00018-5
pmc: PMC11139765
doi:
Types de publication
Journal Article
Langues
eng
Pagination
100286Informations de copyright
© 2024 The Authors. Published by Elsevier Inc.
Déclaration de conflit d'intérêts
They have no conflict interests.