External auditory canal metastasis revealing bronchogenic carcinoma: A case report and literature review.

Ear canal adenocarcinoma bronchial carcinoma chemoradiation neoplasm metastasis

Journal

SAGE open medical case reports
ISSN: 2050-313X
Titre abrégé: SAGE Open Med Case Rep
Pays: England
ID NLM: 101638686

Informations de publication

Date de publication:
2024
Historique:
received: 27 11 2023
accepted: 10 05 2024
medline: 3 6 2024
pubmed: 3 6 2024
entrez: 3 6 2024
Statut: epublish

Résumé

This report presents a rare case of bronchogenic adenocarcinoma with initial metastasis in the external auditory canal. The patient, a 64-year-old man with a history of bladder urothelial carcinoma, initially presented with a persistent right otitis externa. Otoscopic examination revealed a mass obstructing the right external auditory canal. The temporal bone computed tomography scan revealed a mass that completely obstructed the right external auditory canal and extended into the middle ear. A biopsy showed a poorly differentiated adenocarcinoma of bronchogenic origin, confirmed by positive immunohistochemical staining for cytokeratin 7 and Thyroid transcription factor-1. Further imaging revealed a large tumor mass in the lung involving the mediastinum and parenchyma, along with carcinomatous lymphangitis and cerebral metastasis. Histopathological examination of the primary lung tumor confirmed a poorly differentiated adenocarcinoma with similar features to the metastasis in the external auditory canal. The tumor was staged as T4N2M1c, and the patient underwent local external-beam radiation therapy with chemotherapy.

Identifiants

pubmed: 38828381
doi: 10.1177/2050313X241258155
pii: 10.1177_2050313X241258155
pmc: PMC11143865
doi:

Types de publication

Case Reports

Langues

eng

Pagination

2050313X241258155

Informations de copyright

© The Author(s) 2024.

Déclaration de conflit d'intérêts

The author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.

Auteurs

Sirine Ayadi (S)

ENT Department and Research Laboratory LR23ES01, Habib Bourguiba University Hospital, University of Sfax, Sfax, Tunisia.
Faculty of Medicine of Sfax, Tunisia.

Omar Walha (O)

ENT Department and Research Laboratory LR23ES01, Habib Bourguiba University Hospital, University of Sfax, Sfax, Tunisia.
Faculty of Medicine of Sfax, Tunisia.

Rania Kharrat (R)

ENT Department and Research Laboratory LR23ES01, Habib Bourguiba University Hospital, University of Sfax, Sfax, Tunisia.
Faculty of Medicine of Sfax, Tunisia.

Mariem Ben Ayed (M)

ENT Department and Research Laboratory LR23ES01, Habib Bourguiba University Hospital, University of Sfax, Sfax, Tunisia.
Faculty of Medicine of Sfax, Tunisia.

Boutheina Hammami (B)

ENT Department and Research Laboratory LR23ES01, Habib Bourguiba University Hospital, University of Sfax, Sfax, Tunisia.
Faculty of Medicine of Sfax, Tunisia.

Mohamed Amine Chaabouni (MA)

ENT Department and Research Laboratory LR23ES01, Habib Bourguiba University Hospital, University of Sfax, Sfax, Tunisia.
Faculty of Medicine of Sfax, Tunisia.

Ilhem Charfeddine (I)

ENT Department and Research Laboratory LR23ES01, Habib Bourguiba University Hospital, University of Sfax, Sfax, Tunisia.
Faculty of Medicine of Sfax, Tunisia.

Classifications MeSH