Epidemiology of hip fractures in Thailand.
Cost
Epidemiology
Hip fractures
Incidence
Osteoporosis
Thailand
Journal
Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA
ISSN: 1433-2965
Titre abrégé: Osteoporos Int
Pays: England
ID NLM: 9100105
Informations de publication
Date de publication:
04 Jun 2024
04 Jun 2024
Historique:
received:
16
11
2023
accepted:
23
05
2024
medline:
4
6
2024
pubmed:
4
6
2024
entrez:
4
6
2024
Statut:
aheadofprint
Résumé
This retrospective study examining hip fracture incidence, hip fracture trends, and the annual hospitalization costs for hip fractures in a population aged 50 years and older within the Universal Health Coverage System revealed that the incidence of hip fractures and the annual hospitalization costs for hip fractures increased significantly from 2013 to 2022. To examine the annual incidence of hip fractures over 10 years (2013-2022), hip fracture trends, and the annual hospitalization costs for hip fractures in a population aged 50 years and older within the Universal Health Coverage System. A retrospective study was conducted. Hip fracture hospitalizations were identified using ICD-10. Data on the number of hip fracture hospitalizations, population aged ≥ 50 years, and hospitalization costs were obtained. The primary outcome was the annual incidence of hip fractures. The secondary outcomes were hip fracture incidence by 5-year age group, the annual hospitalization costs for hip fractures, and the number of hip fractures in 6 regions of Thailand. The hip fracture incidence increased annually from 2013-2019 and then plateaued from 2019-2022, with the crude incidence (per 100,000 population) increasing from 112.7 in 2013 to 146.7 in 2019 and 146.9 in 2022. The age-standardized incidence (per 100,000 population) increased from 116.3 in 2013 to 145.1 in 2019 and remained at 140.7 in 2022. Increases in the crude incidence were observed in both sexes (34% in females and 21% in males; p < 0.05). The annual hospitalization costs for hip fractures increased 2.5-fold, from 17.3 million USD in 2013 to 42.8 million USD in 2022 (p < 0.001). The number of hip fractures increased in all six regions of Thailand across the 10-year study period. Osteoporotic hip fractures are a significant health concern in Thailand. The incidence and the annual hospitalization costs for hip fractures increased significantly from 2013 to 2022.
Identifiants
pubmed: 38832991
doi: 10.1007/s00198-024-07140-2
pii: 10.1007/s00198-024-07140-2
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Informations de copyright
© 2024. International Osteoporosis Foundation and Bone Health and Osteoporosis Foundation.
Références
Feng JN, Zhang CG, Li BH, Zhan SY, Wang SF, Song CL (2023) Global burden of hip fracture: The Global Burden of Disease Study. Osteoporos Int 35:41–52
doi: 10.1007/s00198-023-06907-3
pubmed: 37704919
Dyer SM, Crotty M, Fairhall N, Magaziner J, Beaupre LA, Cameron ID, Sherrington C (2016) A critical review of the long-term disability outcomes following hip fracture. BMC Geriatr 16:158
doi: 10.1186/s12877-016-0332-0
pubmed: 27590604
pmcid: 5010762
Johnell O, Kanis JA (2004) An estimate of the worldwide prevalence, mortality and disability associated with hip fracture. Osteoporos Int 15:897–902
doi: 10.1007/s00198-004-1627-0
pubmed: 15490120
Sing CW, Lin TC, Bartholomew S et al (2023) Global Epidemiology of Hip Fractures: Secular Trends in Incidence Rate, Post-Fracture Treatment, and All-Cause Mortality. J Bone Miner Res 38:1064–1075
doi: 10.1002/jbmr.4821
pubmed: 37118993
Kanis JA, Oden A, McCloskey EV, Johansson H, Wahl DA, Cooper C, Epidemiology IOFWGo, Quality of L (2012) A systematic review of hip fracture incidence and probability of fracture worldwide. Osteoporos Int 23:2239-2256
Cauley JA, Chalhoub D, Kassem AM, Fuleihan Gel H (2014) Geographic and ethnic disparities in osteoporotic fractures. Nat Rev Endocrinol 10:338–351
doi: 10.1038/nrendo.2014.51
pubmed: 24751883
Dimai HP, Reichardt B, Zitt E, Concin H, Malle O, Fahrleitner-Pammer A, Svedbom A, Brozek W (2022) Thirty years of hip fracture incidence in Austria: is the worst over? Osteoporos Int 33:97–104
doi: 10.1007/s00198-021-06086-z
pubmed: 34392387
Ormeño JC, Martínez R, Frías C, Von Plessing C, Quevedo I (2022) Decreasing hip fracture rates among older adults in Chile, 2001–2019. Arch Osteoporos 17:26
doi: 10.1007/s11657-022-01067-z
pubmed: 35091883
Meyer AC, Ek S, Drefahl S, Ahlbom A, Hedström M, Modig K (2021) Trends in Hip Fracture Incidence, Recurrence, and Survival by Education and Comorbidity: A Swedish Register-based Study. Epidemiology 32:425–433
doi: 10.1097/EDE.0000000000001321
pubmed: 33512961
pmcid: 8011509
Søgaard AJ, Holvik K, Meyer HE, Tell GS, Gjesdal CG, Emaus N, Grimnes G, Schei B, Forsmo S, Omsland TK (2016) Continued decline in hip fracture incidence in Norway: a NOREPOS study. Osteoporos Int 27:2217–2222
doi: 10.1007/s00198-016-3516-8
pubmed: 26902091
Pueyo-Sánchez MJ, Larrosa M, Suris X, Casado E, Auleda J, Fusté J, Ortún V (2017) Secular trend in the incidence of hip fracture in Catalonia, Spain, 2003–2014. Age Ageing 46:324–328
pubmed: 27810855
Chen FP, Shyu YC, Fu TS, Sun CC, Chao AS, Tsai TL, Huang TS (2017) Secular trends in incidence and recurrence rates of hip fracture: a nationwide population-based study. Osteoporos Int 28:811–818
doi: 10.1007/s00198-016-3820-3
pubmed: 27832325
Nordstrom P, Bergman J, Ballin M, Nordstrom A (2022) Trends in Hip Fracture Incidence, Length of Hospital Stay, and 30-Day Mortality in Sweden from 1998–2017: A Nationwide Cohort Study. Calcif Tissue Int 111:21–28
doi: 10.1007/s00223-022-00954-4
pubmed: 35166892
pmcid: 9232476
Zhang C, Feng J, Wang S et al (2020) Incidence of and trends in hip fracture among adults in urban China: A nationwide retrospective cohort study. PLoS Med 17:e1003180
doi: 10.1371/journal.pmed.1003180
pubmed: 32760065
pmcid: 7410202
Lewiecki EM, Wright NC, Curtis JR, Siris E, Gagel RF, Saag KG, Singer AJ, Steven PM, Adler RA (2018) Hip fracture trends in the United States, 2002 to 2015. Osteoporos Int 29:717–722
doi: 10.1007/s00198-017-4345-0
pubmed: 29282482
Hou XL, Liu JY, Fan XH et al (2022) Secular trends of incidence and hospitalization cost of hip fracture in Tangshan, China. Osteoporos Int 33:89–96
doi: 10.1007/s00198-021-06050-x
pubmed: 34235549
Charatcharoenwitthaya N, Jaisamrarn U, Songpatanasilp T et al (2023) Summary of the Thai Osteoporosis Foundation (TOPF) Clinical Practice Guideline on the diagnosis and management of osteoporosis 2021. Osteoporos Sarcopenia 9:45–52
doi: 10.1016/j.afos.2023.06.001
pubmed: 37496989
pmcid: 10366425
Rojanasthien S, Luevitoonvechkij S (2005) Epidemiology of hip fracture in Chiang Mai. J Med Assoc Thai 88(Suppl 5):S105-109
pubmed: 16871663
Wongtriratanachai P, Luevitoonvechkij S, Songpatanasilp T, Sribunditkul S, Leerapun T, Phadungkiat S, Rojanasthien S (2013) Increasing incidence of hip fracture in Chiang Mai, Thailand. J Clin Densitom 16:347–352
doi: 10.1016/j.jocd.2012.07.002
pubmed: 22906626
Sucharitpongpan W, Daraphongsataporn N, Saloa S, Philawuth N, Chonyuen P, Sriruanthong K, Waiwattana K (2019) Epidemiology of fragility hip fractures in Nan, Thailand. Osteoporos Sarcopenia 5:19–22
doi: 10.1016/j.afos.2019.03.003
pubmed: 31008374
pmcid: 6452923
Forsén L, Søgaard AJ, Holvik K, Meyer HE, Omsland TK, Stigum H, Dahl C (2020) Geographic variations in hip fracture incidence in a high-risk country stretching into the Arctic: a NOREPOS study. Osteoporos Int 31:1323–1331
doi: 10.1007/s00198-020-05346-8
pubmed: 32095840
pmcid: 7280325
Stroup NE, Freni-Titulaer LW, Schwartz JJ (1990) Unexpected geographic variation in rates of hospitalization for patients who have fracture of the hip. Medicare enrollees in the United States. J Bone Joint Surg Am 72:1294–1298
doi: 10.2106/00004623-199072090-00003
pubmed: 2229103
Barbier S, Ecochard R, Schott AM, Colin C, Delmas PD, Jaglal SB, Couris CM (2009) Geographical variations in hip fracture risk for women: strong effects hidden in standardised ratios. Osteoporos Int 20:371–377
doi: 10.1007/s00198-008-0687-y
pubmed: 18636217
Tamaki J, Fujimori K, Ikehara S, Kamiya K, Nakatoh S, Okimoto N, Ogawa S, Ishii S, Iki M (2019) Estimates of hip fracture incidence in Japan using the National Health Insurance Claim Database in 2012–2015. Osteoporos Int 30:975–983
doi: 10.1007/s00198-019-04844-8
pubmed: 30648192
Wu TY, Hu HY, Lin SY, Chie WC, Yang RS, Liaw CK (2017) Trends in hip fracture rates in Taiwan: a nationwide study from 1996 to 2010. Osteoporos Int 28:653–665
doi: 10.1007/s00198-016-3783-4
pubmed: 27858121
Lo JC, Yang W, Park-Sigal JJ, Ott SM (2023) Osteoporosis and Fracture Risk among Older US Asian Adults. Curr Osteoporos Rep 21:592–608
doi: 10.1007/s11914-023-00805-7
pubmed: 37542683
Ballane G, Cauley JA, Luckey MM, Fuleihan Gel H (2014) Secular trends in hip fractures worldwide: opposing trends East versus West. J Bone Miner Res 29:1745–1755
doi: 10.1002/jbmr.2218
pubmed: 24644018
Svedbom A, Hadji P, Hernlund E, Thoren R, McCloskey E, Stad R, Stollenwerk B (2019) Cost-effectiveness of pharmacological fracture prevention for osteoporosis as prescribed in clinical practice in France, Germany, Italy, Spain, and the United Kingdom. Osteoporos Int 30:1745–1754
doi: 10.1007/s00198-019-05064-w
pubmed: 31270592
Li N, Cornelissen D, Silverman S et al (2021) An Updated Systematic Review of Cost-Effectiveness Analyses of Drugs for Osteoporosis. Pharmacoeconomics 39:181–209
doi: 10.1007/s40273-020-00965-9
pubmed: 33026634
Nayak S, Greenspan SL (2020) Cost-effectiveness of five versus ten years of alendronate treatment prior to drug holiday for women with osteoporosis. Osteoporos Int 31:1273–1282
doi: 10.1007/s00198-019-05258-2
pubmed: 32020265
pmcid: 8215100