Extracellular fluid excess linked to reduced choroidal vascularity index in patients with chronic kidney disease.
Journal
Scientific reports
ISSN: 2045-2322
Titre abrégé: Sci Rep
Pays: England
ID NLM: 101563288
Informations de publication
Date de publication:
04 06 2024
04 06 2024
Historique:
received:
14
09
2023
accepted:
29
05
2024
medline:
5
6
2024
pubmed:
5
6
2024
entrez:
4
6
2024
Statut:
epublish
Résumé
Extracellular fluid (ECF) excess is common in patients with chronic kidney disease (CKD). This study (involving 284 patients with CKD) explored the association between choroidal vascularity index (CVI) and ECF excess. We categorised patients into three groups based on extracellular water/total body water: normal, mildly overhydrated, and severely overhydrated. The more severe ECF status was associated with a lower CVI after adjustment (B = - 0.902, p = 0.001). In non-diabetic patients, both vascular luminal (LA, p < 0.001) and stromal areas (SA, p = 0.003) were significantly reduced in patients with severe ECF excess compared to others, whereas diabetic patients showed no significant differences in LA (p = 0.96) and SA (p = 0.86) based on ECF excess status. These findings suggest that ECF status may influence CVI in patients with CKD, underscoring the need for further research to clarify its direct impact on choroidal changes.
Identifiants
pubmed: 38834727
doi: 10.1038/s41598-024-63444-7
pii: 10.1038/s41598-024-63444-7
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
12769Subventions
Organisme : Faculty research grant from Yonsei University College of Medicine
ID : 6-2023-0160
Organisme : Faculty research grant from Yonsei University College of Medicine
ID : 6-2023-0160
Organisme : Faculty research grant from Yonsei University College of Medicine
ID : 6-2023-0160
Organisme : Faculty research grant from Yonsei University College of Medicine
ID : 6-2023-0160
Organisme : Faculty research grant from Yonsei University College of Medicine
ID : 6-2023-0160
Organisme : Faculty research grant from Yonsei University College of Medicine
ID : 6-2023-0160
Informations de copyright
© 2024. The Author(s).
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