Low rate hippocampal delay period activity encodes behavioral experience.
CA1
CA3
adversarial attacks
decoding
hippocampus
working memory
Journal
Hippocampus
ISSN: 1098-1063
Titre abrégé: Hippocampus
Pays: United States
ID NLM: 9108167
Informations de publication
Date de publication:
05 Jun 2024
05 Jun 2024
Historique:
revised:
08
04
2024
received:
16
10
2023
accepted:
09
05
2024
medline:
5
6
2024
pubmed:
5
6
2024
entrez:
5
6
2024
Statut:
aheadofprint
Résumé
Remembering what just happened is a crucial prerequisite to form long-term memories but also for establishing and maintaining working memory. So far there is no general agreement about cortical mechanisms that support short-term memory. Using a classifier-based decoding approach, we report that hippocampal activity during few sparsely distributed brief time intervals contains information about the previous sensory motor experience of rodents. These intervals are characterized by only a small increase of firing rate of only a few neurons. These low-rate predictive patterns are present in both working memory and non-working memory tasks, in two rodent species, rats and Mongolian gerbils, are strongly reduced for rats with medial entorhinal cortex lesions, and depend on the familiarity of the sensory-motor context.
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : German Research Association
ID : LE2250/12-1
Organisme : German Research Association
ID : LE2250/20-1
Organisme : NIH HHS
ID : R01 NS086947
Pays : United States
Organisme : NIH HHS
ID : R01MH119179
Pays : United States
Organisme : German Research Association
ID : INST 39/963-1 FUGG
Informations de copyright
© 2024 The Author(s). Hippocampus published by Wiley Periodicals LLC.
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