Contexts of care for people with differences of sex development: Diversity is still missing in the laboratory routine.


Journal

Medizinische Genetik : Mitteilungsblatt des Berufsverbandes Medizinische Genetik e.V
ISSN: 1863-5490
Titre abrégé: Med Genet
Pays: Germany
ID NLM: 9440651

Informations de publication

Date de publication:
Sep 2023
Historique:
pmc-release: 16 08 2024
medline: 6 6 2024
pubmed: 6 6 2024
entrez: 6 6 2024
Statut: epublish

Résumé

The 2006 Chicago consensus statement of management of disorders/difference of sex development (DSD) has achieved advantages in clinical care and diagnosis for patients and families affect by DSD. This article provides a brief overview of contexts of care for physicians, and points out specific challenges in clinical practice that have arisen from the transformations of the sex/gender system in recent years. We focus on the impact of diagnosis and laboratory measurements. Both laboratory measurements and hormonal therapies still depend on the binary system. One problem is the lack of reference intervals for the different forms of DSD, which means that diversity is often neglected. In the following, we will give a brief insight into this complex topic.

Identifiants

pubmed: 38840817
doi: 10.1515/medgen-2023-2037
pii: medgen-2023-2037
pmc: PMC10842577
doi:

Types de publication

Journal Article

Langues

eng

Pagination

181-187

Informations de copyright

© 2023 the author(s), published by De Gruyter.

Auteurs

Alexandra E Kulle (AE)

Campus Kiel/Christian-Albrechts University of Kiel Division of Pediatric Endocrinology and Diabetes, Department of children and adolescent medicine I, University Hospital of Schleswig-Holstein Rosalind-Franklin-Str 9 24105 Kiel Germany.

Martina Jürgensen (M)

Campus Lübeck/University of Lübeck Division of Pediatric Endocrinology and Diabetes, Department of Pediatrics, University-Hospital of Schleswig-Holstein Lübeck Germany.

Ulla Döhnert (U)

Campus Lübeck/University of Lübeck Division of Pediatric Endocrinology and Diabetes, Department of Pediatrics, University-Hospital of Schleswig-Holstein Lübeck Germany.

Lisa Malich (L)

University of Lübeck Institute for the History of Medicine and Science Studies Lübeck Germany.

Louise Marshall (L)

Campus Lübeck/University of Lübeck Division of Pediatric Endocrinology and Diabetes, Department of Pediatrics, University-Hospital of Schleswig-Holstein Lübeck Germany.

Olaf Hiort (O)

Campus Lübeck/University of Lübeck Division of Pediatric Endocrinology and Diabetes, Department of Pediatrics, University-Hospital of Schleswig-Holstein Lübeck Germany.

Classifications MeSH