Conversion to open surgery in obese patients undergoing minimally invasive distal pancreatectomy: results from a multicenter analysis.


Journal

HPB : the official journal of the International Hepato Pancreato Biliary Association
ISSN: 1477-2574
Titre abrégé: HPB (Oxford)
Pays: England
ID NLM: 100900921

Informations de publication

Date de publication:
29 May 2024
Historique:
received: 30 01 2024
revised: 08 04 2024
accepted: 27 05 2024
medline: 10 6 2024
pubmed: 10 6 2024
entrez: 9 6 2024
Statut: aheadofprint

Résumé

Although minimally invasive distal pancreatectomy (MIDP) is considered a standard approach it still presents a non-negligible rate of conversion to open that is mainly related to some difficulty factors, as obesity. The aim of this study is to analyze the preoperative factors associated with conversion in obese patients with MIDP. In this multicenter study, all obese patients who underwent MIDP at 18 international expert centers were included. The preoperative factors associated with conversion to open surgery were analyzed. Out of 436 patients, 91 (20.9%) underwent conversion to open, presenting higher blood loss, longer operative time and similar rate of major complications. Twenty (22%) patients received emergent conversion. At univariate analysis, the type of approach, radiological invasion of adjacent organs, preoperative enlarged lymphnodes and ASA ≥ III were significantly associated with conversion to open. At multivariate analysis, robotic approach showed a significantly lower conversion rate (14.6 % vs 27.3%, OR = 2.380, p = 0.001). ASA ≥ III (OR = 2.391, p = 0.002) and preoperative enlarged lymphnodes (OR = 3.836, p = 0.003) were also independently associated with conversion. Conversion rate is significantly lower in patients undergoing robotic approach. Radiological enlarged lymphnodes and ASA ≥ III are also associated with conversion to open. Conversion is associated with poorer perioperative outcomes, especially in case of intraoperative hemorrhage.

Sections du résumé

BACKGROUND BACKGROUND
Although minimally invasive distal pancreatectomy (MIDP) is considered a standard approach it still presents a non-negligible rate of conversion to open that is mainly related to some difficulty factors, as obesity. The aim of this study is to analyze the preoperative factors associated with conversion in obese patients with MIDP.
METHODS METHODS
In this multicenter study, all obese patients who underwent MIDP at 18 international expert centers were included. The preoperative factors associated with conversion to open surgery were analyzed.
RESULTS RESULTS
Out of 436 patients, 91 (20.9%) underwent conversion to open, presenting higher blood loss, longer operative time and similar rate of major complications. Twenty (22%) patients received emergent conversion. At univariate analysis, the type of approach, radiological invasion of adjacent organs, preoperative enlarged lymphnodes and ASA ≥ III were significantly associated with conversion to open. At multivariate analysis, robotic approach showed a significantly lower conversion rate (14.6 % vs 27.3%, OR = 2.380, p = 0.001). ASA ≥ III (OR = 2.391, p = 0.002) and preoperative enlarged lymphnodes (OR = 3.836, p = 0.003) were also independently associated with conversion.
CONCLUSION CONCLUSIONS
Conversion rate is significantly lower in patients undergoing robotic approach. Radiological enlarged lymphnodes and ASA ≥ III are also associated with conversion to open. Conversion is associated with poorer perioperative outcomes, especially in case of intraoperative hemorrhage.

Identifiants

pubmed: 38853075
pii: S1365-182X(24)01742-8
doi: 10.1016/j.hpb.2024.05.016
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Informations de copyright

Copyright © 2024. Published by Elsevier Ltd.

Auteurs

Fabio Ausania (F)

Department of HBP Surgery and Transplantation, General and Digestive Surgery, Hospital Clinic Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Spain; Facultat de Medicina i Ciències de la Salut, Universitat de Barcelona (UB), Barcelona, Spain.

Carolina Gonzalez-Abós (C)

Department of HBP Surgery and Transplantation, General and Digestive Surgery, Hospital Clinic Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Spain; Facultat de Medicina i Ciències de la Salut, Universitat de Barcelona (UB), Barcelona, Spain. Electronic address: carol.gonzaleza@gmail.com.

Filippo Landi (F)

Department of HBP Surgery and Transplantation, General and Digestive Surgery, Hospital Clinic Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Spain; Facultat de Medicina i Ciències de la Salut, Universitat de Barcelona (UB), Barcelona, Spain.

John B Martinie (JB)

Division of HPB Surgery, Department of Surgery, Carolinas Medical Center, Charlotte, NC, USA.

Dionisios Vrochides (D)

Division of HPB Surgery, Department of Surgery, Carolinas Medical Center, Charlotte, NC, USA.

Matthew Walsh (M)

HPB Surgery Department, Digestive Disease and Surgery Institute, Cleveland Clinic, Cleveland, OH, USA.

Shanaz M Hossain (SM)

HPB Surgery Department, Digestive Disease and Surgery Institute, Cleveland Clinic, Cleveland, OH, USA.

Steven White (S)

Freeman Hospital, NHS, Newcastle-Upon-Tyne, UK.

Viswakumar Prabakaran (V)

Freeman Hospital, NHS, Newcastle-Upon-Tyne, UK.

Laleh G Melstrom (LG)

Division of Surgical Oncology, Gastrointestinal Disease Team, City of Hope Medical Center, Duarte, CA, USA.

Yuman Fong (Y)

Division of Surgical Oncology, Gastrointestinal Disease Team, City of Hope Medical Center, Duarte, CA, USA.

Giovanni Butturini (G)

Department of HBP Surgery, P. Pederzoli Hospital, Peschiera del Garda, Italy.

Laura Bignotto (L)

Department of HBP Surgery, P. Pederzoli Hospital, Peschiera del Garda, Italy.

Valentina Valle (V)

Division of General, Minimally Invasive and Robotic Surgery, Department of Surgery, University of Illinois at Chicago, Chicago, IL, USA.

Yuntao Bing (Y)

Department of General Surgery, Beijing Third Hospital, Beijing, China.

Dianrong Xiu (D)

Department of General Surgery, Beijing Third Hospital, Beijing, China.

Gregorio Di Franco (G)

Division of Translational and New Technologies in Medicine and Surgery, General Surgery Department, University of Pisa, Pisa, Italy.

Francisco Sanchez-Bueno (F)

Department of HBP Surgery, Virgen de la Arrixaca Hospital, Murcia, Spain.

Nicola de'Angelis (N)

Department of Digestive, HBP Surgery and Liver Transplantation, Henri Mondor Hospital, APHP, Creteil, France.

Alexis Laurent (A)

Department of Digestive, HBP Surgery and Liver Transplantation, Henri Mondor Hospital, APHP, Creteil, France.

Giuseppe Giuliani (G)

Division of General and Minimally Invasive Surgery, Misericordia Hospital, Grosseto, Italy.

Graziano Pernazza (G)

General and Robotic Surgery Department, San Giovanni Hospital, Rome, Italy.

Alessandro Esposito (A)

HBP Surgery Department, Policlinico G.B. Rossi Hospital, Verona, Italy.

Roberto Salvia (R)

HBP Surgery Department, Policlinico G.B. Rossi Hospital, Verona, Italy.

Francesca Bazzocchi (F)

Department of HBP Surgery, IRCCS Casa Sollievo della Soferenza Hospital, Foggia, Italy.

Ludovica Esposito (L)

Department of HBP Surgery, IRCCS Casa Sollievo della Soferenza Hospital, Foggia, Italy.

Andrea Pietrabissa (A)

Department of HBP Surgery, Policlinico S. Matteo Hospital, Pavia, Italy.

Luigi Pugliese (L)

Department of HBP Surgery, Policlinico S. Matteo Hospital, Pavia, Italy.

Riccardo Memeo (R)

Department of Surgery, Acquaviva delle Fonti Hospital, Bari, Italy.

Ichiro Uyama (I)

Department of Surgery, Fujita Health University School of Medicine, Toyoake, Japan.

Yuichiro Uchida (Y)

Department of Surgery, Fujita Health University School of Medicine, Toyoake, Japan.

José Ríos (J)

Department of Clinical Pharmacology, Hospital Clinic and Medical Statistics Core Facility, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Biostatistics Unit, Faculty of Medicine, Universitat Autònoma de Barcelona (UAB), Barcelona, Spain.

Andrea Coratti (A)

Division of General and Minimally Invasive Surgery, Misericordia Hospital, Grosseto, Italy.

Luca Morelli (L)

Division of Translational and New Technologies in Medicine and Surgery, General Surgery Department, University of Pisa, Pisa, Italy.

Pier C Giulianotti (PC)

Division of General, Minimally Invasive and Robotic Surgery, Department of Surgery, University of Illinois at Chicago, Chicago, IL, USA.

Classifications MeSH