Intraoral Salivary Gland Cystadenomas: A Case Series Study and Literature Review.
Mouth neoplasms
Mucinous cystadenoma
Papillary cystadenoma
Salivary gland neoplasms
Journal
Head and neck pathology
ISSN: 1936-0568
Titre abrégé: Head Neck Pathol
Pays: United States
ID NLM: 101304010
Informations de publication
Date de publication:
09 Jun 2024
09 Jun 2024
Historique:
received:
25
04
2024
accepted:
28
05
2024
medline:
10
6
2024
pubmed:
10
6
2024
entrez:
9
6
2024
Statut:
epublish
Résumé
Salivary gland cystadenoma (SGCA) is a rare benign tumor that predominantly occurs in the parotid gland. SGCAs affecting the minor salivary glands are uncommon and often resemble, clinically and histopathologically, other salivary gland lesions. This study aimed to describe a series of four cases of SGCA affecting intraoral sites and performed a literature review of well-reported SGCA published in the English-language literature. SGCA cases included in this series were diagnosed in the buccal mucosa, lip, and hard palate of female patients aged between 19 and 78 years. All cases underwent excisional biopsy and were histologically characterized by a multicystic growth with variable degrees of capsule formation and were lined by several types of epithelium, including some cell types that are infrequently reported in SGCA. In some cases, a small collection of lymphocytes was observed adjacent to cystic formations. All SGCA were positive for periodic acid-Schiff, and immunohistochemical reactions were positive for CK7 and p63. The follow-up time ranged widely from 3 to 53 months, and to date, no recurrence has been observed. The literature review revealed a total of 33 published studies accounting for 55 SGCA cases.
Sections du résumé
BACKGROUND
BACKGROUND
Salivary gland cystadenoma (SGCA) is a rare benign tumor that predominantly occurs in the parotid gland. SGCAs affecting the minor salivary glands are uncommon and often resemble, clinically and histopathologically, other salivary gland lesions.
METHODS
METHODS
This study aimed to describe a series of four cases of SGCA affecting intraoral sites and performed a literature review of well-reported SGCA published in the English-language literature.
RESULTS
RESULTS
SGCA cases included in this series were diagnosed in the buccal mucosa, lip, and hard palate of female patients aged between 19 and 78 years. All cases underwent excisional biopsy and were histologically characterized by a multicystic growth with variable degrees of capsule formation and were lined by several types of epithelium, including some cell types that are infrequently reported in SGCA. In some cases, a small collection of lymphocytes was observed adjacent to cystic formations. All SGCA were positive for periodic acid-Schiff, and immunohistochemical reactions were positive for CK7 and p63. The follow-up time ranged widely from 3 to 53 months, and to date, no recurrence has been observed.
CONCLUSION
CONCLUSIONS
The literature review revealed a total of 33 published studies accounting for 55 SGCA cases.
Identifiants
pubmed: 38853193
doi: 10.1007/s12105-024-01661-2
pii: 10.1007/s12105-024-01661-2
doi:
Types de publication
Journal Article
Review
Case Reports
Langues
eng
Sous-ensembles de citation
IM
Pagination
45Subventions
Organisme : Coordenação de Aperfeiçoamento de Pessoal de Nível Superior - Brasil (CAPES)
ID : Finance Code 001
Organisme : Coordenação de Aperfeiçoamento de Pessoal de Nível Superior - Brasil (CAPES)
ID : Finance Code 001
Organisme : Coordenação de Aperfeiçoamento de Pessoal de Nível Superior - Brasil (CAPES)
ID : Finance Code 001
Informations de copyright
© 2024. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.
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