Cage effects on synaptic plasticity and its modulation in a mouse model of fragile X syndrome.

Animals Fragile X Syndrome / physiopathology Mice Fragile X Mental Retardation Protein / genetics Neuronal Plasticity Mice, Knockout Receptors, N-Methyl-D-Aspartate / metabolism Disease Models, Animal Long-Term Potentiation Male Mice, Inbred C57BL Housing, Animal Fear
CFC Fmr1 LTP NMDAR PAM STP littermate syndrome

Journal

Philosophical transactions of the Royal Society of London. Series B, Biological sciences
ISSN: 1471-2970
Titre abrégé: Philos Trans R Soc Lond B Biol Sci
Pays: England
ID NLM: 7503623

Informations de publication

Date de publication:
29 Jul 2024
Historique:
medline: 10 6 2024
pubmed: 10 6 2024
entrez: 10 6 2024
Statut: ppublish

Résumé

Fragile X syndrome (FXS) is characterized by impairments in executive function including different types of learning and memory. Long-term potentiation (LTP), thought to underlie the formation of memories, has been studied in the

Identifiants

DOI: 10.1098/rstb.2023.0484 PMID: 38853552
pubmed: 38853552
doi: 10.1098/rstb.2023.0484
doi:

Substances chimiques

Fragile X Mental Retardation Protein 139135-51-6
Fmr1 protein, mouse 0
Receptors, N-Methyl-D-Aspartate 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

20230484

Subventions

Organisme : CIHR
Pays : Canada

Auteurs

Rasa Volianskis (R)

Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Sinai Health System, Toronto, Ontario M5G 1X5, Canada.
Department of Physiology, University of Toronto, Toronto, Ontario M5S 1A8, Canada.
ORCID: 0000-0002-1447-4878

Camilla J Lundbye (CJ)

Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Sinai Health System, Toronto, Ontario M5G 1X5, Canada.
Department of Physiology, University of Toronto, Toronto, Ontario M5S 1A8, Canada.
ORCID: 0000-0001-5863-4557

Gillian N Petroff (GN)

Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Sinai Health System, Toronto, Ontario M5G 1X5, Canada.
Department of Physiology, University of Toronto, Toronto, Ontario M5S 1A8, Canada.
ORCID: 0000-0001-5019-8949

David E Jane (DE)

Hello Bio Limited, Cabot Park, Avonmouth, Bristol BS11 0QL, UK.

John Georgiou (J)

Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Sinai Health System, Toronto, Ontario M5G 1X5, Canada.
TANZ Centre for Research in Neurodegenerative Diseases, University of Toronto, Toronto, Ontario M5S 1A8, Canada.
ORCID: 0000-0003-4503-6384

Graham L Collingridge (GL)

Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Sinai Health System, Toronto, Ontario M5G 1X5, Canada.
Department of Physiology, University of Toronto, Toronto, Ontario M5S 1A8, Canada.
TANZ Centre for Research in Neurodegenerative Diseases, University of Toronto, Toronto, Ontario M5S 1A8, Canada.
ORCID: 0000-0002-9572-5359

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Cage effects on synaptic plasticity and its...
questionsmedicales.fr › Malformations et maladies congénitales, héréditaires et néonatales › Maladies génétiques congénitales › Maladies neurodégénératives héréditaires › Retard mental lié à l'X › Syndrome du chromosome X fragile › Cage effects on synaptic plasticity and its...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › Cage effects on synaptic plasticity and its...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Nucléoprotéines › Protéines de liaison à l'ARN › Protéine du syndrome X fragile › Cage effects on synaptic plasticity and its...
questionsmedicales.fr › Phénomènes physiologiques de l'appareil locomoteur et du système nerveux › Phénomènes physiologiques du système nerveux › Plasticité neuronale › Cage effects on synaptic plasticity and its...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › Souris transgéniques › Souris knockout › Cage effects on synaptic plasticity and its...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines membranaires › Récepteurs de surface cellulaire › Récepteurs aux neuromédiateurs › Récepteurs aux acides aminés › Récepteurs au glutamate › Récepteurs ionotropes du glutamate › Récepteurs du N-méthyl-D-aspartate › Cage effects on synaptic plasticity and its...
questionsmedicales.fr › Techniques d'investigation › Modèles théoriques › Modèles biologiques › Modèles animaux de maladie humaine › Cage effects on synaptic plasticity and its...
questionsmedicales.fr › Phénomènes physiologiques de l'appareil locomoteur et du système nerveux › Phénomènes physiologiques du système nerveux › Plasticité neuronale › Potentialisation à long terme › Cage effects on synaptic plasticity and its...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › Lignées consanguines de souris › Souris de lignée C57BL › Cage effects on synaptic plasticity and its...
questionsmedicales.fr › Environnement et santé publique › Environnement › Environnement contrôlé › Hébergement animal › Cage effects on synaptic plasticity and its...
questionsmedicales.fr › Comportement et mécanismes comportementaux › Émotions › Peur › Cage effects on synaptic plasticity and its...