Strategic enzymatic enantioselective desymmetrization of prochiral cyclohexa-2,5-dienones.

Journal

Chemical communications (Cambridge, England)
ISSN: 1364-548X
Titre abrégé: Chem Commun (Camb)
Pays: England
ID NLM: 9610838

Informations de publication

Date de publication:
10 Jun 2024
Historique:
medline: 10 6 2024
pubmed: 10 6 2024
entrez: 10 6 2024
Statut: aheadofprint

Résumé

Asymmetric desymmetrization through the selective reduction of one double bond of prochiral 2,5-cyclohexadienones is highly challenging. A novel method has been developed for synthesizing chiral cyclohexenones by employing an ene-reductase (

Identifiants

DOI: 10.1039/d4cc02181a PMID: 38856301
pubmed: 38856301
doi: 10.1039/d4cc02181a
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Auteurs

Bhavita Kattula (B)

Department of Applied Biology, Hyderabad, India. anthony@csiriict.in.
Academy of Scientific and Innovative Research (AcSIR), Ghaziabad-201002, India.
ORCID: 0000-0003-3884-2003

Anandarao Munakala (A)

Department of Organic Synthesis and Process Chemistry, Hyderabad, Telangana, India. rchegondi@iict.res.in.

Rajnandani Kashyap (R)

Department of Applied Biology, Hyderabad, India. anthony@csiriict.in.

Tarun Nallamilli (T)

Department of Organic Synthesis and Process Chemistry, Hyderabad, Telangana, India. rchegondi@iict.res.in.
Academy of Scientific and Innovative Research (AcSIR), Ghaziabad-201002, India.

Narendra Kumar Nagendla (NK)

Department of Analytical and Structural Chemistry, CSIR-Indian Institute of Chemical Technology, Hyderabad-500 007, Telangana, India.
Academy of Scientific and Innovative Research (AcSIR), Ghaziabad-201002, India.

Surabhi Naza (S)

Department of Applied Biology, Hyderabad, India. anthony@csiriict.in.
Academy of Scientific and Innovative Research (AcSIR), Ghaziabad-201002, India.

Mohana Krishna Reddy Mudiam (MKR)

Department of Analytical and Structural Chemistry, CSIR-Indian Institute of Chemical Technology, Hyderabad-500 007, Telangana, India.
Academy of Scientific and Innovative Research (AcSIR), Ghaziabad-201002, India.

Rambabu Chegondi (R)

Department of Organic Synthesis and Process Chemistry, Hyderabad, Telangana, India. rchegondi@iict.res.in.
Academy of Scientific and Innovative Research (AcSIR), Ghaziabad-201002, India.
ORCID: 0000-0003-2072-7429

Anthony Addlagatta (A)

Department of Applied Biology, Hyderabad, India. anthony@csiriict.in.
Academy of Scientific and Innovative Research (AcSIR), Ghaziabad-201002, India.

Classifications MeSH