Comparison of Patients Operated for Lumbar Spinal Stenosis with and without Spondylolisthesis - A Secondary Analysis of the NORDSTEN Trials.

Journal

Spine
ISSN: 1528-1159
Titre abrégé: Spine (Phila Pa 1976)
Pays: United States
ID NLM: 7610646

Informations de publication

Date de publication:
11 Jun 2024
Historique:
received: 11 03 2024
accepted: 27 04 2024
medline: 10 6 2024
pubmed: 10 6 2024
entrez: 10 6 2024
Statut: aheadofprint

Résumé

Observational cohort study (secondary analysis of two randomized trials). To investigate whether function, disability, pain and quality of life before surgery and patient-reported outcome as well as complication and reoperation rates up to two years after surgery differ between lumbar spinal stenosis patients with and without spondylolisthesis. Lumbar spinal stenosis is a degenerative condition of the spine, which appears with or without degenerative spondylolisthesis often presenting similar signs and symptoms. This study is a secondary analysis of two randomized trials on patients with lumbar spinal stenosis with and without spondylolisthesis conducted at 16 public Norwegian hospitals. Disability, function, back pain, leg pain, quality of life, complication and reoperation rates up to two years after surgery were compared between the two cohorts. A total of 704 patients were included in this study, 267 patients with spondylolisthesis (median age 67.0 years [IQR 61.0-72.0]; 68.7% female) and 437 patients without spondylolisthesis (median age 68.0 years IQR 62.0-73.0]; 52.9% female). In the linear mixed model analysis there were no significant differences in disability, function, back pain, leg pain and quality of life scores between the two cohorts of patient with and without spondylolisthesis before surgery or at two years follow-up. The complication rate was 22.9% in patients with spondylolisthesis and 12.1% in patients without spondylolisthesis (P<0.001). There were no significant differences in reoperation rates. In patients with lumbar spinal stenosis the symptom burden before surgery and the clinical outcome up to two years after surgery were similar independently of a concomitant spondylolisthesis.

Sections du résumé

STUDY DESIGN METHODS
Observational cohort study (secondary analysis of two randomized trials).
OBJECTIVE OBJECTIVE
To investigate whether function, disability, pain and quality of life before surgery and patient-reported outcome as well as complication and reoperation rates up to two years after surgery differ between lumbar spinal stenosis patients with and without spondylolisthesis.
SUMMARY OF BACKGROUND DATA BACKGROUND
Lumbar spinal stenosis is a degenerative condition of the spine, which appears with or without degenerative spondylolisthesis often presenting similar signs and symptoms.
METHOD METHODS
This study is a secondary analysis of two randomized trials on patients with lumbar spinal stenosis with and without spondylolisthesis conducted at 16 public Norwegian hospitals. Disability, function, back pain, leg pain, quality of life, complication and reoperation rates up to two years after surgery were compared between the two cohorts.
RESULTS RESULTS
A total of 704 patients were included in this study, 267 patients with spondylolisthesis (median age 67.0 years [IQR 61.0-72.0]; 68.7% female) and 437 patients without spondylolisthesis (median age 68.0 years IQR 62.0-73.0]; 52.9% female). In the linear mixed model analysis there were no significant differences in disability, function, back pain, leg pain and quality of life scores between the two cohorts of patient with and without spondylolisthesis before surgery or at two years follow-up. The complication rate was 22.9% in patients with spondylolisthesis and 12.1% in patients without spondylolisthesis (P<0.001). There were no significant differences in reoperation rates.
CONCLUSION CONCLUSIONS
In patients with lumbar spinal stenosis the symptom burden before surgery and the clinical outcome up to two years after surgery were similar independently of a concomitant spondylolisthesis.

Identifiants

DOI: 10.1097/BRS.0000000000005038 PMID: 38857371
pubmed: 38857371
doi: 10.1097/BRS.0000000000005038
pii: 00007632-990000000-00694
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Informations de copyright

Copyright © 2024 Wolters Kluwer Health, Inc. All rights reserved.

Déclaration de conflit d'intérêts

Conflicts of interest: The authors have no conflicts of interest to report.

Auteurs

Clemens Weber (C)

Department of Neurosurgery, Stavanger University Hospital, Stavanger, Norway.
Department of Quality and Health Technology, University of Stavanger, Stavanger, Norway.

Erland Hermansen (E)

Department of Orthopedic Surgery, Ålesund Hospital, Ålesund, Norway.
Department of Clinical Medicine, University of Bergen, Bergen, Norway.

Tor Åge Myklebust (TÅ)

Department of Research and Innovation, Ålesund Hospital, Ålesund, Norway.

Hasan Banitalebi (H)

Department of Diagnostic Imaging, Akershus University Hospital, Lørenskog, Norway.
Institute of Clinical Medicine, University of Oslo, Oslo, Norway.

Helena Brisby (H)

Department of Orthopedic Surgery, Sahlgrenska University Hospital, Gothenburg, Sweden.
Institute for Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.

Jens Ivar Brox (JI)

Department of Physical Medicine and Rehabilitation, Oslo University Hospital, Oslo, Norway.
Faculty of Medicine, University of Oslo, Oslo, Norway.

Eric Franssen (E)

Department of Orthopedic Surgery, Stavanger University Hospital, Stavanger, Norway.

Christian Hellum (C)

Division of Orthopedic Surgery, Oslo University Hospital, Oslo, Norway.

Kari Indrekvam (K)

Department of Clinical Medicine, University of Bergen, Bergen, Norway.
Kysthospitalet in Hagevik, Orthopedic Clinic, Haukeland University Hospital, Bergen, Norway.

Knut Harboe (K)

Department of Clinical Medicine, University of Bergen, Bergen, Norway.
Department of Orthopedic Surgery, Stavanger University Hospital, Stavanger, Norway.

Frode Rekeland (F)

Department of Clinical Medicine, University of Bergen, Bergen, Norway.
Department of Orthopedic Surgery, Haukeland University Hospital, Bergen, Norway.

Tore Solberg (T)

Department of Neurosurgery, University Hospital of Northern Norway, Tromsø, Norway.
Institute of Clinical Medicine, The Arctic University of Norway, Tromsø, Norway.

Kjersti Storheim (K)

Research and Communication Unit for Musculoskeletal Health, Oslo University Hospital, Oslo, Norway.
Department of Rehabilitation Science and Health Technology, Oslo Metropolitan University, Oslo, Norway.

Ivar Magne Austevoll (IM)

Department of Clinical Medicine, University of Bergen, Bergen, Norway.
Department of Orthopedic Surgery, Haukeland University Hospital, Bergen, Norway.

Classifications MeSH