Closing the policy gap in diabetes care for individuals with advanced CKD.

diabetes model of care integrated diabetes CKD care joint diabetes CKD clinic

Journal

Diabetic medicine : a journal of the British Diabetic Association
ISSN: 1464-5491
Titre abrégé: Diabet Med
Pays: England
ID NLM: 8500858

Informations de publication

Date de publication:
10 Jun 2024
Historique:
received: 23 04 2024
accepted: 28 05 2024
medline: 11 6 2024
pubmed: 11 6 2024
entrez: 11 6 2024
Statut: aheadofprint

Résumé

The co-existence of diabetes and CKD poses significant challenges to healthcare systems, current frameworks often inadequately address the complex needs of individuals with both conditions. Recognising these gaps, we introduced a new diabetes care model for people with advanced CKD in renal satellite units.This paper aims to evaluate this new diabetes model care. We conducted a prospective audit of a new integrated diabetes kidney care model. Data were presented as mean ± SD or counts/percentages, and pre- and post-intervention differences were assessed using paired samples t-tests. A total of 291 individuals with diabetes and advanced CKD stages 4 or 5, or undergoing haemodialysis, were included. The mean age was 68.5 (±13.0) years, 58.4% were males. Nearly half of the cohort had four or more long-term conditions, while two-thirds experienced mild/severe frailty. Only 6% were receiving ongoing diabetes care from secondary care diabetes specialist services. For patients with CKD not receiving dialysis, comparing pre- and post-intervention, there were improvements in HbA1c (-13.0 mmol/mol, p < 0.001), SBP (-13.7 mm Hg, p < 0.0001), and weight (-2.9 kg, p < 0.0001). Furthermore, there was an increase in guideline-directed therapies, with notable usage of SGLT2i (62.9%) and GLP1-RA (28.4%), while access to diabetes technology increased to 89%. This new model of care resulted in improved metabolic outcomes, increased utilisation of guideline-directed therapies, and enhanced access to diabetes technologies. However, the model also revealed significant unmet clinical needs in areas such as access to diabetes care, diabetes eye screening and foot surveillance.

Identifiants

pubmed: 38859547
doi: 10.1111/dme.15381
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

e15381

Informations de copyright

© 2024 The Author(s). Diabetic Medicine published by John Wiley & Sons Ltd on behalf of Diabetes UK.

Références

Phillips K, Hazlehurst JM, Sheppard C, et al. Inequalities in the management of diabetic kidney disease in UK primary care: a cross‐sectional analysis of a large primary care database. Diabet Med. 2024;41:e15153.
UK Renal Registry. UK Renal Registry 24th Annual Report—Data to 31/12/2020. UK Kidney Association; 2022:2022.
JBDS. Management of Adults with Diabetes on Dialysis. JBDS; 2023.
Ali S, Alicea S, Avery L, et al. Best practice in the delivery of diabetes care in the primary care network. 2021.
Habte‐Asres HH, Murrells T, Nitsch D, Wheeler DC, Forbes A. Glycaemic variability and progression of chronic kidney disease in people with diabetes and comorbid kidney disease: retrospective cohort study. Diabetes Res Clin Pract. 2022;193:110117.
Habte‐Asres HH, Jiang Y, Rosenthal M, Wheeler DC. Burden of impaired awareness of hypoglycemia in people with diabetes undergoing hemodialysis. BMJ Open Diabetes Res Care. 2024;12(1):e003730.
NICE. Type 2 Diabetes in Adults: Management. 2022. National Institute Clinical Excellence; 2022.
NICE. Chronic Kidney Disease: Assessment and Management. National Institute Clinical Excellence; 2021.
ABCD, Managing Hyperglycaemia in Patients with Diabetes and Diabetic Nephropathy‐Chronic Kidney Disease. 2021.
NHS Digital. Report 1: Care Processes and Treatment Targets, 2022–2023. 2023. National Diabetes Audit.
Cushley LN, Quinn NB, Blows P, McKeever E, Peto T. The integration of diabetic eye screening into hemodialysis units in Northern Ireland. Kidney 360. 2022;3(9):1542‐1544.
Lee WJ, Sobrin L, Kang MH, et al. Ischemic diabetic retinopathy as a possible prognostic factor for chronic kidney disease progression. Eye (Lond). 2014;28(9):1119‐1125.
Ndip A, Rutter MK, Vileikyte L, et al. Dialysis treatment is an independent risk factor for foot ulceration in patients with diabetes and stage 4 or 5 chronic kidney disease. Diabetes Care. 2010;33(8):1811‐1816.
Joseph K, Avari P, Goldet G, et al. The impact of diabetes specialist nurses' in‐reach service on people with diabetes on haemodialysis: a pilot study ‘education to protect tomorrow’. Diabet Med. 2024;11:e15306.
Wijewickrama P, Onyema M, Eid H, et al. Standards of diabetes care and burden of hypoglycaemia in people with diabetes on peritoneal dialysis: results from a real‐world clinical audit. Perit Dial Int. 2024;44:216‐220.
NHS. Guidance for the Implementation of Flash Glucose Monitoring Prescribing Across the NHS in London. London Diabetes Clinical Network and NHS London: London; 2018.
Hannah KL, Nemlekar PM, Johnson ML, Cherñavvsky DR, Norman GJ. Continuous glucose monitors and reduced diabetes‐related hospitalizations in patients with type 2 diabetes and chronic kidney disease. Kidney 360. 2024;5:515‐521. doi:10.34067/KID.0000000000000396
Habte‐Asres H, Harbour M, Rosenthal M. Audit of the pilot clinic for kidney transplant recipients with diabetes. In IDF conference 2022.
Lo C, Zimbudzi E, Teede H, et al. Models of care for co‐morbid diabetes and chronic kidney disease. Nephrol Ther. 2018;23(8):711‐717.
Zimbudzi E, Lo C, Ranasinha S, et al. A co‐designed integrated kidney and diabetes model of care improves mortality, glycaemic control and self‐care. Nephrol Dial Transplant. 2021;37(8):1472‐1481.
Idowu O, Jayashekara A, Chequer S, et al. A Comparison between the Joint Renal Diabetes Clinic and General Diabetes Clinics in a District General Hospital. 2017. ENHIDE.
Jayapaul MK, Messersmith R, Bennett‐Jones DN, Mead PA, Large DM. The joint diabetic‐renal clinic in clinical practice: 10 years of data from a District General Hospital. J Assoc Phys. 2006;99(3):153‐160.
Low S, Lim SC, Wang J, et al. Long‐term outcomes of patients with type 2 diabetes attending a multidisciplinary diabetes kidney disease clinic. J Diabetes. 2018;10(7):572‐580.
NHS‐England. NHS long term plan. 2019.

Auteurs

Hellena Hailu Habte-Asres (HH)

Florence Nightingale Faculty of Nursing, Midwifery and Palliative Care, King's College London, London, UK.
Royal Free London, NHS Foundation Trust, London, UK.

Miranda Rosenthal (M)

King's College Hospital, London, UK.

Dorothea Nitsch (D)

Royal Free London, NHS Foundation Trust, London, UK.
Department of Non-Communicable Disease Epidemiology, Faculty of Epidemiology and Population Health, London School of Hygiene & Tropical Medicine, London, UK.

David C Wheeler (DC)

Royal Free London, NHS Foundation Trust, London, UK.
UCL Department of Renal Medicine, University College London, London, UK.

Classifications MeSH