Involvement of

biomarker breast cancer muscle cells myoepithelial cells the cancer genome atlas tumor suppressor

Journal

Frontiers in cell and developmental biology
ISSN: 2296-634X
Titre abrégé: Front Cell Dev Biol
Pays: Switzerland
ID NLM: 101630250

Informations de publication

Date de publication:
2024
Historique:
received: 16 09 2023
accepted: 22 04 2024
medline: 11 6 2024
pubmed: 11 6 2024
entrez: 11 6 2024
Statut: epublish

Résumé

Patients with breast cancer show altered expression of genes within the pectoralis major skeletal muscle cells of the breast. Through analyses of The Cancer Genome Atlas (TCGA)-breast cancer (BRCA), we identified three previously uncharacterized putative novel tumor suppressor genes expressed in normal muscle cells, whose expression was downregulated in breast tumors. We found that NEDD4 binding protein 2-like 1 (

Identifiants

pubmed: 38859961
doi: 10.3389/fcell.2024.1295403
pii: 1295403
pmc: PMC11163233
doi:

Types de publication

Journal Article

Langues

eng

Pagination

1295403

Informations de copyright

Copyright © 2024 Dastsooz, Anselmi, Lauria, Cicconetti, Proserpio, Mohammadisoleimani, Firoozi, Mansoori, Haghi-Aminjan, Caizzi and Oliviero.

Déclaration de conflit d'intérêts

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Auteurs

Hassan Dastsooz (H)

Department of Life Sciences and Systems Biology, University of Turin, Turin, Italy.
IIGM-Italian Institute for Genomic Medicine, IRCCS, Candiolo, TO, Italy.
Candiolo Cancer Institute, FPO-IRCCS, Candiolo Cancer (IT), Torino, Italy.

Francesca Anselmi (F)

Department of Life Sciences and Systems Biology, University of Turin, Turin, Italy.

Andrea Lauria (A)

Department of Life Sciences and Systems Biology, University of Turin, Turin, Italy.

Chiara Cicconetti (C)

Department of Life Sciences and Systems Biology, University of Turin, Turin, Italy.

Valentina Proserpio (V)

Department of Life Sciences and Systems Biology, University of Turin, Turin, Italy.

Elham Mohammadisoleimani (E)

Department of Medical Biotechnology, Fasa University of Medical Sciences, Fasa, Iran.

Zahra Firoozi (Z)

Department of Medical Genetics, Fasa University of Medical Sciences, Fasa, Iran.

Yaser Mansoori (Y)

Department of Medical Genetics, Fasa University of Medical Sciences, Fasa, Iran.
Noncommunicable Diseases Research Center, Fasa University of Medical Sciences, Fasa, Iran.

Hamed Haghi-Aminjan (H)

Pharmaceutical Sciences Research Center, Ardabil University of Medical Sciences, Ardabil, Iran.

Livia Caizzi (L)

Department of Life Sciences and Systems Biology, University of Turin, Turin, Italy.

Salvatore Oliviero (S)

Department of Life Sciences and Systems Biology, University of Turin, Turin, Italy.
IIGM-Italian Institute for Genomic Medicine, IRCCS, Candiolo, TO, Italy.
Candiolo Cancer Institute, FPO-IRCCS, Candiolo Cancer (IT), Torino, Italy.

Classifications MeSH