A deep learning model for generating [

Amyloid Deep learning Metabolism Neuroimaging PET

Journal

European journal of nuclear medicine and molecular imaging
ISSN: 1619-7089
Titre abrégé: Eur J Nucl Med Mol Imaging
Pays: Germany
ID NLM: 101140988

Informations de publication

Date de publication:
11 Jun 2024
Historique:
received: 01 02 2024
accepted: 05 05 2024
medline: 11 6 2024
pubmed: 11 6 2024
entrez: 11 6 2024
Statut: aheadofprint

Résumé

Amyloid-β (Aβ) plaques is a significant hallmark of Alzheimer's disease (AD), detectable via amyloid-PET imaging. The Fluorine-18-Fluorodeoxyglucose ([ A total of 166 subjects including cognitively unimpaired individuals (N = 72), subjects with mild cognitive impairment (N = 73) and dementia (N = 21) were included in this study. All underwent T1-weighted MRI, dual-phase amyloid PET scans using either Fluorine-18 Florbetapir ([ The clinical evaluation showed that, in comparison to eFBP/eFMM (average of clinical similarity score (CSS) = 1.53), the synthetic [ We proposed a DL model for generating the [

Identifiants

DOI: 10.1007/s00259-024-06755-1 PMID: 38861183
pubmed: 38861183
doi: 10.1007/s00259-024-06755-1
pii: 10.1007/s00259-024-06755-1
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung
ID : SNSF 320030_176052

Informations de copyright

© 2024. The Author(s).

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Auteurs

Amirhossein Sanaat (A)

Division of Nuclear Medicine and Molecular Imaging, Geneva University Hospital, Geneva, Switzerland. Amirhossein.sanaat@unige.ch.

Cecilia Boccalini (C)

Division of Nuclear Medicine and Molecular Imaging, Geneva University Hospital, Geneva, Switzerland. cecilia.boccalini@unige.ch.
Laboratory of Neuroimaging and Innovative Molecular Tracers (NIMTlab), Geneva University Neurocenter and Faculty of Medicine, University of Geneva, Geneva, Switzerland. cecilia.boccalini@unige.ch.

Gregory Mathoux (G)

Division of Nuclear Medicine and Molecular Imaging, Geneva University Hospital, Geneva, Switzerland.

Daniela Perani (D)

Vita-Salute San Raffaele University, Nuclear Medicine Unit San Raffaele Hospital, Milan, Italy.

Giovanni B Frisoni (GB)

Memory Clinic, Geneva University Hospitals, Geneva, Switzerland.

Sven Haller (S)

CIMC - Centre d'Imagerie Médicale de Cornavin, Geneva, Switzerland.
Faculty of Medicine, University of Geneva, Geneva, Switzerland.

Marie-Louise Montandon (ML)

Department of Rehabilitation and Geriatrics, Geneva University Hospitals and University of Geneva, Geneva, Switzerland.

Cristelle Rodriguez (C)

Division of Institutional Measures, Medical Direction, Geneva University Hospitals, Geneva, Switzerland.

Panteleimon Giannakopoulos (P)

Division of Institutional Measures, Medical Direction, Geneva University Hospitals, Geneva, Switzerland.
Department of Psychiatry, Faculty of Medicine, University of Geneva, Geneva, Switzerland.

Valentina Garibotto (V)

Division of Nuclear Medicine and Molecular Imaging, Geneva University Hospital, Geneva, Switzerland.
Laboratory of Neuroimaging and Innovative Molecular Tracers (NIMTlab), Geneva University Neurocenter and Faculty of Medicine, University of Geneva, Geneva, Switzerland.
CIBM Center for Biomedical Imaging, Geneva, Switzerland.

Habib Zaidi (H)

Division of Nuclear Medicine and Molecular Imaging, Geneva University Hospital, Geneva, Switzerland. habib.zaidi@hcuge.ch.
Department of Nuclear Medicine and Molecular Imaging, University of Groningen, Groningen, Netherlands. habib.zaidi@hcuge.ch.
Department of Nuclear Medicine, University of Southern Denmark, Odense, Denmark. habib.zaidi@hcuge.ch.
University Research and Innovation Center, Óbudabuda University, Budapest, Hungary. habib.zaidi@hcuge.ch.
ORCID: 0000-0001-7559-5297

Classifications MeSH