Seroprevalence study in humans and molecular detection in Rhipicephalus sanguineus ticks of severe fever with thrombocytopenia syndrome virus in Thailand.
Animals
Thailand
/ epidemiology
Seroepidemiologic Studies
Rhipicephalus sanguineus
/ virology
Humans
Phlebovirus
/ genetics
Middle Aged
Female
Male
Adult
Severe Fever with Thrombocytopenia Syndrome
/ epidemiology
Dogs
Aged
Adolescent
Antibodies, Viral
/ blood
Young Adult
Child
Child, Preschool
Aged, 80 and over
Infant
Immunoglobulin G
/ blood
Rhipicephalus sanguineus
SFTSV
Seroprevalence
Thailand
Tick-borne diseases
Journal
Scientific reports
ISSN: 2045-2322
Titre abrégé: Sci Rep
Pays: England
ID NLM: 101563288
Informations de publication
Date de publication:
11 Jun 2024
11 Jun 2024
Historique:
received:
05
02
2024
accepted:
06
06
2024
medline:
12
6
2024
pubmed:
12
6
2024
entrez:
11
6
2024
Statut:
epublish
Résumé
Severe fever with thrombocytopenia syndrome virus (SFTSV) is an emerging tick-borne virus with a mortality rate of up to 30%. First identified in China in 2009, it was later reported in other Asian countries, including Thailand in 2020. SFTSV has been detected in several tick species, including Rhipicephalus sanguineus, known for infesting dogs. We conducted a seroprevalence study of SFTSV in Bangkok and Nong Khai, Thailand, by analyzing 1162 human samples collected between 2019 and 2023. The testing method relied on IgG detection using ELISA and confirmed though a virus seroneutralization test. The results indicated that out of the participants, 12 (1.1%) tested positive for anti-SFTSV IgG antibodies; however, none exhibited positive results in the seroneutralization assay. Additionally, molecular detection of SFTSV, Crimean-Congo hemorrhagic fever (CCHF), Coxiella spp., Bartonella spp., and Rickettsia spp. was performed on 433 Rh. sanguineus ticks collected from 49 dogs in 2023 in Chachoengsao Province, Thailand. No evidence of these pathogens was found in ticks. These findings highlight the importance of exploring viral cross-reactivity. Furthermore, it is important to conduct additional studies to isolate SFTSV from animals and ticks in order to identify the potential transmission routes contributing to human and animal infections in Thailand.
Identifiants
pubmed: 38862576
doi: 10.1038/s41598-024-64242-x
pii: 10.1038/s41598-024-64242-x
doi:
Substances chimiques
Antibodies, Viral
0
Immunoglobulin G
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
13397Subventions
Organisme : Office of the Permanent Secretary, Ministry of Higher Education, Science, Research and Innovation (OPS MHESI), Thailand Science Research and Innovation (TSRI)
ID : RGNS 64-172
Informations de copyright
© 2024. The Author(s).
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