Progesterone and 17-hydroxy-progesterone concentrations in follicular fluid and serum reflect their production in granulosa and theca cells.

17-OH-progesterone Granulosa cells Human ovarian steroidogenesis Ovarian stimulation Progesterone Theca cells

Journal

Reproductive biomedicine online
ISSN: 1472-6491
Titre abrégé: Reprod Biomed Online
Pays: Netherlands
ID NLM: 101122473

Informations de publication

Date de publication:
30 Jan 2024
Historique:
received: 02 11 2023
revised: 18 01 2024
accepted: 24 01 2024
medline: 13 6 2024
pubmed: 13 6 2024
entrez: 12 6 2024
Statut: aheadofprint

Résumé

How is the production of progesterone (P Three cohorts were examined: (i) 31 women undergoing natural and stimulated cycles, with serum hormone measurements taken every 3 days; (ii) 50 women undergoing ovarian stimulation, with hormone concentrations in serum and follicular fluid assessed at five time points during final follicle maturation; and (iii) 12 women undergoing fertility preservation, with hormone concentrations evaluated via the follicular fluid of small antral follicles. In the early follicular phase, theca cells primarily synthesized 17-OH-P The P

Identifiants

DOI: 10.1016/j.rbmo.2024.103853 PMID: 38865783
pubmed: 38865783
pii: S1472-6483(24)00042-7
doi: 10.1016/j.rbmo.2024.103853
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

103853

Informations de copyright

Copyright © 2024 The Author(s). Published by Elsevier Ltd.. All rights reserved.

Auteurs

M Zheng (M)

Laboratory of Reproductive Biology, Copenhagen University Hospital, Copenhagen, Denmark; Department of Clinical Medicine, Faculty of Health and Medical Science, University of Copenhagen, Copenhagen, Denmark. Electronic address: mengxue.zheng@regionh.dk.

L C Poulsen (LC)

The Fertility Clinic, Herlev Hospital, Herlev, Denmark.

N F Wang (NF)

The Fertility Clinic, Copenhagen University Hospital, Copenhagen, Denmark.

L S Mamsen (LS)

Laboratory of Reproductive Biology, Copenhagen University Hospital, Copenhagen, Denmark.

M L Johannsen (ML)

Laboratory of Reproductive Biology, Copenhagen University Hospital, Copenhagen, Denmark; Toxicology and Drug Metabolism Group, Department of Pharmacy, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.

B Styrishave (B)

Toxicology and Drug Metabolism Group, Department of Pharmacy, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.

M L Grøndahl (ML)

The Fertility Clinic, Herlev Hospital, Herlev, Denmark.

K Løssl (K)

The Fertility Clinic, Copenhagen University Hospital, Copenhagen, Denmark.

A L M Englund (ALM)

The Fertility Clinic, Zealand University Hospital, Køge, Denmark.

S O Skouby (SO)

The Fertility Clinic, Herlev Hospital, Herlev, Denmark.

C Y Andersen (CY)

Department of Clinical Medicine, Faculty of Health and Medical Science, University of Copenhagen, Copenhagen, Denmark; The Fertility Clinic, Herlev Hospital, Herlev, Denmark. Electronic address: cya@yding.com.

Classifications MeSH