Comparison of the overall survival of different treatment methods in patients with Muscle-invasive bladder cancer: A retrospective study.

Radical cystectomy bladder cancer bladder preservation chemotherapy oncology radiotherapy survival rate trimodal therapy urology

Journal

Urologia
ISSN: 1724-6075
Titre abrégé: Urologia
Pays: United States
ID NLM: 0417372

Informations de publication

Date de publication:
12 Jun 2024
Historique:
medline: 13 6 2024
pubmed: 13 6 2024
entrez: 13 6 2024
Statut: aheadofprint

Résumé

Bladder-Sparing Approach was presented in patients who are not willing or not suitable for Radical Cystectomy (RC). There have been inconsistencies in the literature regarding the comparison of survival rates of these two methods. Our objective is to evaluate the survival rate of patients with muscle-invasive bladder cancer (MIBC) undergoing different treatment methods. Retrospective cross-sectional study. A secondary care, multicenter study in Kerman, Iran 2008 to 2016. All 200 patients who were diagnosed with Muscle Invasive Bladder Cancer and were admitted to our hospitals. Patients with inaccessible medical files and patients with pathologies other than TCC were excluded. Radical cystectomy and different methods of bladder preservation were compared based on their survival rate. Radical cystectomy or bladder preservation. Overall survival of the patients was 2 years [95% CI: 1.37-2.63]. The overall 5-year survival rate of patients with MIBC was 32%. Having a 6.4 years overall survival, the RC group showed the highest survival compared with others ( The Bladder-Preservation method, as a replacement for RC, showed a lower overall survival rate in our study. A prospective randomized clinical trial may declare the best treatment.

Identifiants

pubmed: 38867469
doi: 10.1177/03915603241256009
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

3915603241256009

Déclaration de conflit d'intérêts

Declaration of conflicting interestsThe author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.

Auteurs

Hamid Pakmanesh (H)

Department of Urology, School of Medicine, Shahid Bahonar Hospital, Kerman University of Medical Sciences, Kerman, Iran.

Azadeh Khajehsalimi (A)

Department of Urology, School of Medicine, Shahid Bahonar Hospital, Kerman University of Medical Sciences, Kerman, Iran.

Mohammadamin Hesamarefi (M)

Department of Urology, School of Medicine, Shahid Bahonar Hospital, Kerman University of Medical Sciences, Kerman, Iran.

Mohamad Reza Ebadzadeh (MR)

Department of Urology, School of Medicine, Shahid Bahonar Hospital, Kerman University of Medical Sciences, Kerman, Iran.

Azam Bazrafshan (A)

Neuroscience Research Center, Institute of Neuropharmacology, Kerman University of Medical Sciences, Kerman, Iran.

Reza Malekpourafshar (R)

Pathology and Stem Cell Research Center, Kerman University of Medical Sciences, Kerman, Iran.

Mahboubeh Mirzaei (M)

Department of Urology, School of Medicine, Shahid Bahonar Hospital, Kerman University of Medical Sciences, Kerman, Iran.

Azar Daneshpajouh (A)

Department of Urology, School of Medicine, Shahid Bahonar Hospital, Kerman University of Medical Sciences, Kerman, Iran.

Armita Shahesmaeili (A)

Department of Urology, School of Medicine, Shahid Bahonar Hospital, Kerman University of Medical Sciences, Kerman, Iran.

Nazanin Eslami (N)

Department of Urology, School of Medicine, Shahid Bahonar Hospital, Kerman University of Medical Sciences, Kerman, Iran.

Classifications MeSH