Idiopathic basal ganglia calcification presenting with obsessive-compulsive symptoms: A case report.
Fahr's disease
idiopathic basal ganglia calcification
obsessive‐compulsive symptoms
Journal
PCN reports : psychiatry and clinical neurosciences
ISSN: 2769-2558
Titre abrégé: PCN Rep
Pays: Australia
ID NLM: 9918451287106676
Informations de publication
Date de publication:
Mar 2024
Mar 2024
Historique:
received:
23
10
2023
revised:
12
12
2023
accepted:
15
12
2023
medline:
13
6
2024
pubmed:
13
6
2024
entrez:
13
6
2024
Statut:
epublish
Résumé
Idiopathic basal ganglia calcification (IBGC), also known as Farh's disease, is a rare neurodegenerative disorder characterized by calcification of the basal ganglia and other brain regions. This disease usually occurs in middle-aged patients and presents with various neurological and psychiatric symptoms. The exact prevalence is unknown; however, population genomic data analysis suggests a prevalence of at least 4.5/10,000 to 3.3/1000, indicating that the disease is more common than previously thought and remains underdiagnosed. We report the case of a middle-aged Japanese man who attempted suicide twice because of obsessive-compulsive ideation caused by trivial triggers. The patient's psychiatric symptoms resolved relatively quickly after hospitalization, and imaging and genetic testing led to a diagnosis of IBGC. This case report illustrates the importance of including IBGC in the differential diagnosis of psychiatric symptoms that initially develop in middle-aged patients.
Sections du résumé
Background
UNASSIGNED
Idiopathic basal ganglia calcification (IBGC), also known as Farh's disease, is a rare neurodegenerative disorder characterized by calcification of the basal ganglia and other brain regions. This disease usually occurs in middle-aged patients and presents with various neurological and psychiatric symptoms. The exact prevalence is unknown; however, population genomic data analysis suggests a prevalence of at least 4.5/10,000 to 3.3/1000, indicating that the disease is more common than previously thought and remains underdiagnosed.
Case Presentation
UNASSIGNED
We report the case of a middle-aged Japanese man who attempted suicide twice because of obsessive-compulsive ideation caused by trivial triggers. The patient's psychiatric symptoms resolved relatively quickly after hospitalization, and imaging and genetic testing led to a diagnosis of IBGC.
Conclusion
UNASSIGNED
This case report illustrates the importance of including IBGC in the differential diagnosis of psychiatric symptoms that initially develop in middle-aged patients.
Identifiants
pubmed: 38868467
doi: 10.1002/pcn5.166
pii: PCN5166
pmc: PMC11114289
doi:
Types de publication
Case Reports
Journal Article
Langues
eng
Pagination
e166Informations de copyright
© 2024 The Authors. Psychiatry and Clinical Neurosciences Reports published by John Wiley & Sons Australia, Ltd on behalf of Japanese Society of Psychiatry and Neurology.
Déclaration de conflit d'intérêts
The authors declare no conflict of interest.