Idiopathic basal ganglia calcification presenting with obsessive-compulsive symptoms: A case report.

Fahr's disease idiopathic basal ganglia calcification obsessive‐compulsive symptoms

Journal

PCN reports : psychiatry and clinical neurosciences
ISSN: 2769-2558
Titre abrégé: PCN Rep
Pays: Australia
ID NLM: 9918451287106676

Informations de publication

Date de publication:
Mar 2024
Historique:
received: 23 10 2023
revised: 12 12 2023
accepted: 15 12 2023
medline: 13 6 2024
pubmed: 13 6 2024
entrez: 13 6 2024
Statut: epublish

Résumé

Idiopathic basal ganglia calcification (IBGC), also known as Farh's disease, is a rare neurodegenerative disorder characterized by calcification of the basal ganglia and other brain regions. This disease usually occurs in middle-aged patients and presents with various neurological and psychiatric symptoms. The exact prevalence is unknown; however, population genomic data analysis suggests a prevalence of at least 4.5/10,000 to 3.3/1000, indicating that the disease is more common than previously thought and remains underdiagnosed. We report the case of a middle-aged Japanese man who attempted suicide twice because of obsessive-compulsive ideation caused by trivial triggers. The patient's psychiatric symptoms resolved relatively quickly after hospitalization, and imaging and genetic testing led to a diagnosis of IBGC. This case report illustrates the importance of including IBGC in the differential diagnosis of psychiatric symptoms that initially develop in middle-aged patients.

Sections du résumé

Background UNASSIGNED
Idiopathic basal ganglia calcification (IBGC), also known as Farh's disease, is a rare neurodegenerative disorder characterized by calcification of the basal ganglia and other brain regions. This disease usually occurs in middle-aged patients and presents with various neurological and psychiatric symptoms. The exact prevalence is unknown; however, population genomic data analysis suggests a prevalence of at least 4.5/10,000 to 3.3/1000, indicating that the disease is more common than previously thought and remains underdiagnosed.
Case Presentation UNASSIGNED
We report the case of a middle-aged Japanese man who attempted suicide twice because of obsessive-compulsive ideation caused by trivial triggers. The patient's psychiatric symptoms resolved relatively quickly after hospitalization, and imaging and genetic testing led to a diagnosis of IBGC.
Conclusion UNASSIGNED
This case report illustrates the importance of including IBGC in the differential diagnosis of psychiatric symptoms that initially develop in middle-aged patients.

Identifiants

pubmed: 38868467
doi: 10.1002/pcn5.166
pii: PCN5166
pmc: PMC11114289
doi:

Types de publication

Case Reports Journal Article

Langues

eng

Pagination

e166

Informations de copyright

© 2024 The Authors. Psychiatry and Clinical Neurosciences Reports published by John Wiley & Sons Australia, Ltd on behalf of Japanese Society of Psychiatry and Neurology.

Déclaration de conflit d'intérêts

The authors declare no conflict of interest.

Auteurs

Daisuke Yoshioka (D)

Division of Neuropsychiatry, Faculty of Medicine Tottori University Yonago Japan.

Takehiko Yamanashi (T)

Division of Neuropsychiatry, Faculty of Medicine Tottori University Yonago Japan.

Kenta Taneda (K)

Division of Neurology, Faculty of Medicine Tottori University Yonago Japan.

Takashi Matsukawa (T)

Department of Neurology, Graduate School of Medicine The University of Tokyo Tokyo Japan.

Kenta Orimo (K)

Department of Neurology, Graduate School of Medicine The University of Tokyo Tokyo Japan.

Masaaki Iwata (M)

Division of Neuropsychiatry, Faculty of Medicine Tottori University Yonago Japan.

Classifications MeSH