Safety and Effectiveness of Pulsed Field Ablation for Atrial Fibrillation in Patients with Heart Failure: A MANIFEST-PF Sub-analysis.
Atrial fibrillation
HFPEF
HFREF
heart failure
pulsed field ablation
Journal
JACC. Clinical electrophysiology
ISSN: 2405-5018
Titre abrégé: JACC Clin Electrophysiol
Pays: United States
ID NLM: 101656995
Informations de publication
Date de publication:
08 May 2024
08 May 2024
Historique:
received:
19
04
2024
revised:
01
05
2024
accepted:
01
05
2024
medline:
13
6
2024
pubmed:
13
6
2024
entrez:
13
6
2024
Statut:
aheadofprint
Résumé
Atrial fibrillation (AF) and heart failure (HF) coexist, increasing morbidity and mortality. Studies have demonstrated improved outcomes following AF ablation in HF patients with reduced ejection fraction (EF). To assess the outcomes of pulsed-field ablation (PFA) in HF. MANIFEST-PF is a multicenter patient-level registry of consecutive patients undergoing PFA for paroxysmal (PAF) or persistent AF (PerAF). In this sub-study, patients were stratified as: no history of HF (no-HF), HF with preserved EF (HF Of the 1,381 patients, 85% (n=1,174) were no-HF, 6.2% (n=87) were HF PFA appears to be potentially safe and effective in AF patients with HF. Freedom from atrial arrhythmia post-PFA was higher in patients without a history of HF, with no significant difference between HF subtypes.
Sections du résumé
BACKGROUND
BACKGROUND
Atrial fibrillation (AF) and heart failure (HF) coexist, increasing morbidity and mortality. Studies have demonstrated improved outcomes following AF ablation in HF patients with reduced ejection fraction (EF).
OBJECTIVE
OBJECTIVE
To assess the outcomes of pulsed-field ablation (PFA) in HF.
METHODS
METHODS
MANIFEST-PF is a multicenter patient-level registry of consecutive patients undergoing PFA for paroxysmal (PAF) or persistent AF (PerAF). In this sub-study, patients were stratified as: no history of HF (no-HF), HF with preserved EF (HF
RESULTS
RESULTS
Of the 1,381 patients, 85% (n=1,174) were no-HF, 6.2% (n=87) were HF
CONCLUSION
CONCLUSIONS
PFA appears to be potentially safe and effective in AF patients with HF. Freedom from atrial arrhythmia post-PFA was higher in patients without a history of HF, with no significant difference between HF subtypes.
Identifiants
pubmed: 38869506
pii: S2405-500X(24)00351-7
doi: 10.1016/j.jacep.2024.05.002
pii:
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Informations de copyright
Copyright © 2024. Published by Elsevier Inc.