Risk factors for curable sexually transmitted infections among youth: findings from the STICH population survey in Zimbabwe.

AFRICA Chlamydia Infections Gonorrhea Risk factors TRICHOMONAS

Journal

Sexually transmitted infections
ISSN: 1472-3263
Titre abrégé: Sex Transm Infect
Pays: England
ID NLM: 9805554

Informations de publication

Date de publication:
13 Jun 2024
Historique:
received: 21 02 2024
accepted: 29 05 2024
medline: 14 6 2024
pubmed: 14 6 2024
entrez: 13 6 2024
Statut: aheadofprint

Résumé

Youth are at high risk of sexually transmitted infections (STIs) in Africa. We aimed to determine the risk factors for curable STIs in youth in Zimbabwe. A population-based survey was conducted among randomly selected 18-24 year-olds in 16 communities across two provinces in Zimbabwe to ascertain outcomes for a cluster randomised trial investigating the impact of community-based STI screening for youth on population prevalence of STIs. Participants underwent an interviewer-administered questionnaire, HIV testing and screening for Of the 5601 participants, 62.5% (n=3500) were female, and the median age was 20 (IQR 19-22) years. HIV prevalence was 6.3% (351/5556), and 55.4% (1939/3501) reported condomless sex at last intercourse. Only 7.2% (401/5599) reported STI symptoms, but CT/NG/TV prevalence was 19.8% (1107/5601). On multivariable analysis, factors associated with STI diagnosis included being aged 21-24 years (adjusted OR (aOR) 1.37, 95% CI 1.17 to 1.61); female sex (aOR 2.11, 95% CI 1.76 to 2.53); being unemployed/informally employed (compared with in education/formal employment) (aOR 1.35, 95% CI 1.13 to 1.61); increasing number of sexual partners in the preceding 12 months (one partner: aOR 2.23, 95% CI 1.73 to 2.88; two partners: aOR 2.39, 95% CI 1.69 to 3.39); living with HIV (aOR 1.44, 95% CI 1.07 to 1.94); and previous attempted suicide (aOR 1.58, 95% CI 1.08 to 2.32). The prevalence of STIs among youth in Zimbabwe is high, particularly among those with HIV. In addition to moving away from syndromic STI management and strengthening implementation of existing prevention tools, there is a need for a more holistic focus on broader risk factors such as mental health and employment opportunities, and of integration of HIV and STI programming. ISRCTN15013425, NCT03719521.

Identifiants

pubmed: 38871454
pii: sextrans-2024-056146
doi: 10.1136/sextrans-2024-056146
pii:
doi:

Banques de données

ClinicalTrials.gov
['NCT03719521']

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Informations de copyright

© Author(s) (or their employer(s)) 2024. Re-use permitted under CC BY. Published by BMJ.

Déclaration de conflit d'intérêts

Competing interests: KM is a current editorial fellow at the Sexually Transmitted Infections journal.

Auteurs

Kevin Martin (K)

Clinical Research Department, The London School of Hygiene & Tropical Medicine, London, UK Kevin.Martin@lshtm.ac.uk.
The Health Research Unit Zimbabwe, Biomedical Research and Training Institute, Harare, Zimbabwe.

Ethel Dauya (E)

The Health Research Unit Zimbabwe, Biomedical Research and Training Institute, Harare, Zimbabwe.

Victoria Simms (V)

The Health Research Unit Zimbabwe, Biomedical Research and Training Institute, Harare, Zimbabwe.
MRC International Statistics and Epidemiology Group, Department of Infectious Disease Epidemiology, The London School of Hygiene & Tropical Medicine, London, UK.

Tsitsi Bandason (T)

The Health Research Unit Zimbabwe, Biomedical Research and Training Institute, Harare, Zimbabwe.

Steven Azizi (S)

The Health Research Unit Zimbabwe, Biomedical Research and Training Institute, Harare, Zimbabwe.
MRC International Statistics and Epidemiology Group, Department of Infectious Disease Epidemiology, The London School of Hygiene & Tropical Medicine, London, UK.

Anna Machiha (A)

AIDS and TB Unit, Zimbabwe Ministry of Health and Child Care, Harare, Zimbabwe.

Tinei Shamu (T)

Newlands Clinic, Harare, Zimbabwe.

Primrose Musiyandaka (P)

The Health Research Unit Zimbabwe, Biomedical Research and Training Institute, Harare, Zimbabwe.

Tinashe Mwaturura (T)

The Health Research Unit Zimbabwe, Biomedical Research and Training Institute, Harare, Zimbabwe.

Suzanna C Francis (SC)

MRC International Statistics and Epidemiology Group, Department of Infectious Disease Epidemiology, The London School of Hygiene & Tropical Medicine, London, UK.

Constance R S Mackworth-Young (CRS)

The Health Research Unit Zimbabwe, Biomedical Research and Training Institute, Harare, Zimbabwe.
Department of Global Health and Development, The London School of Hygiene & Tropical Medicine, London, UK.

Joanna Busza (J)

Department of Public Health, Environments and Society, The London School of Hygiene & Tropical Medicine, London, UK.

Constancia Mavodza (C)

The Health Research Unit Zimbabwe, Biomedical Research and Training Institute, Harare, Zimbabwe.
Department of Public Health, Environments and Society, The London School of Hygiene & Tropical Medicine, London, UK.

Mandi Tembo (M)

The Health Research Unit Zimbabwe, Biomedical Research and Training Institute, Harare, Zimbabwe.
MRC International Statistics and Epidemiology Group, Department of Infectious Disease Epidemiology, The London School of Hygiene & Tropical Medicine, London, UK.

Richard J Hayes (RJ)

MRC International Statistics and Epidemiology Group, Department of Infectious Disease Epidemiology, The London School of Hygiene & Tropical Medicine, London, UK.

Katharina Kranzer (K)

Clinical Research Department, The London School of Hygiene & Tropical Medicine, London, UK.
The Health Research Unit Zimbabwe, Biomedical Research and Training Institute, Harare, Zimbabwe.
Division of Infectious Diseases and Tropical Medicine, LMU University Hospital, LMU Munich, Munich, Germany.

Rashida A Ferrand (RA)

Clinical Research Department, The London School of Hygiene & Tropical Medicine, London, UK.
The Health Research Unit Zimbabwe, Biomedical Research and Training Institute, Harare, Zimbabwe.

Chido Dziva Chikwari (C)

The Health Research Unit Zimbabwe, Biomedical Research and Training Institute, Harare, Zimbabwe.
MRC International Statistics and Epidemiology Group, Department of Infectious Disease Epidemiology, The London School of Hygiene & Tropical Medicine, London, UK.

Classifications MeSH