Coexistence of variant-type transthyretin and immunoglobulin light-chain amyloidosis: a case report.

Cardiac amyloidosis Case report Immunoglobulin light-chain amyloidosis Variant-type transthyretin amyloidosis

Journal

European heart journal. Case reports
ISSN: 2514-2119
Titre abrégé: Eur Heart J Case Rep
Pays: England
ID NLM: 101730741

Informations de publication

Date de publication:
Jun 2024
Historique:
received: 12 10 2023
revised: 08 05 2024
accepted: 23 05 2024
medline: 14 6 2024
pubmed: 14 6 2024
entrez: 14 6 2024
Statut: epublish

Résumé

Determining the type of amyloid deposits is clinically important for choosing the specific therapies for cardiac amyloidosis. A 78-year-old woman who had been experiencing fluid retention and dyspnoea on exertion for 6 months was referred to our hospital for the management of heart failure with left ventricular hypertrophy. Since Coexistence of ATTRv and AL within cardiac amyloidosis is extremely uncommon. In situations where incongruities arise between the amyloid type determined via immunohistochemistry findings and the amyloid type assumed based on other clinical findings, mass spectrometry should be considered.

Sections du résumé

Background UNASSIGNED
Determining the type of amyloid deposits is clinically important for choosing the specific therapies for cardiac amyloidosis.
Case summary UNASSIGNED
A 78-year-old woman who had been experiencing fluid retention and dyspnoea on exertion for 6 months was referred to our hospital for the management of heart failure with left ventricular hypertrophy. Since
Discussion UNASSIGNED
Coexistence of ATTRv and AL within cardiac amyloidosis is extremely uncommon. In situations where incongruities arise between the amyloid type determined via immunohistochemistry findings and the amyloid type assumed based on other clinical findings, mass spectrometry should be considered.

Identifiants

pubmed: 38872953
doi: 10.1093/ehjcr/ytae264
pii: ytae264
pmc: PMC11171424
doi:

Types de publication

Case Reports Journal Article

Langues

eng

Pagination

ytae264

Informations de copyright

© The Author(s) 2024. Published by Oxford University Press on behalf of the European Society of Cardiology.

Déclaration de conflit d'intérêts

Conflict of interest: None declared.

Auteurs

Yuko Eda (Y)

Department of Cardiovascular Medicine, Kitasato University School of Medicine, 1-15-1 Kitasato, Minami-Ku, Sagamihara, Kanagawa 252-0374, Japan.

Shunsuke Ishii (S)

Department of Cardiovascular Medicine, Kitasato University School of Medicine, 1-15-1 Kitasato, Minami-Ku, Sagamihara, Kanagawa 252-0374, Japan.

Suzuho Onagi (S)

Institute for Biomedical Sciences, Shinshu University, Matsumoto, Nagano, Japan.

Nagaaki Katoh (N)

Department of Medicine (Neurology and Rheumatology), Shinshu University School of Medicine, Matsumoto, Nagano, Japan.

Junya Ako (J)

Department of Cardiovascular Medicine, Kitasato University School of Medicine, 1-15-1 Kitasato, Minami-Ku, Sagamihara, Kanagawa 252-0374, Japan.

Classifications MeSH