Examining patient demographics and major adverse cardiac events following noncardiac surgery: Applying a health equity lens.

Cardiac surgery Disparities Ethnicity MACE Perioperative Race

Journal

Cardiovascular revascularization medicine : including molecular interventions
ISSN: 1878-0938
Titre abrégé: Cardiovasc Revasc Med
Pays: United States
ID NLM: 101238551

Informations de publication

Date de publication:
10 Jun 2024
Historique:
received: 10 05 2024
revised: 04 06 2024
accepted: 05 06 2024
medline: 15 6 2024
pubmed: 15 6 2024
entrez: 14 6 2024
Statut: aheadofprint

Résumé

Major adverse cardiac events (MACE) are a major contributor to postoperative complications. This study employed a health equity lens to examine rates of postoperative MACE by race and ethnicity. This single-center, retrospective observational cohort study followed patients with and without pre-existing coronary artery stents from 2008 to 2018 who underwent non-cardiac surgery. MACE was the primary outcome (death, acute MI, repeated coronary revascularization, in-stent thrombosis) and self-reported race and ethnicity was the primary predictor. A propensity score model of a 1:1 cohort of non-Hispanic White (NHW) patients and all other racial and ethnic minority populations (Hispanic and Black) was used to compare the rate of perioperative MACE in this cohort. During the study period, 79,686 cases were included in the analytic sample; 950 patients (1.2 %) had pre-existing coronary artery stents. <1 % of patients experienced MACE within 30 days following non-cardiac surgery (0.8 %). After confounder adjustment and propensity score matching, there were no statistically significant differences in MACE among racial and ethnic minority patients compared to NHW patients (OR = 0.77; 95 % CI: 0.48, 1.25). In our sensitivity analyses, stratifying by sex, there were no differences in MACE by race and ethnicity. The study found no statistically significant differences in MACE by race and ethnicity among patients who underwent non-cardiac surgery. Access to a high-volume, high-quality hospital such as the one studied may reduce the presence of healthcare disparities and may explain why our findings are not consistent with previous studies.

Sections du résumé

BACKGROUND BACKGROUND
Major adverse cardiac events (MACE) are a major contributor to postoperative complications. This study employed a health equity lens to examine rates of postoperative MACE by race and ethnicity.
METHODS METHODS
This single-center, retrospective observational cohort study followed patients with and without pre-existing coronary artery stents from 2008 to 2018 who underwent non-cardiac surgery. MACE was the primary outcome (death, acute MI, repeated coronary revascularization, in-stent thrombosis) and self-reported race and ethnicity was the primary predictor. A propensity score model of a 1:1 cohort of non-Hispanic White (NHW) patients and all other racial and ethnic minority populations (Hispanic and Black) was used to compare the rate of perioperative MACE in this cohort.
RESULTS RESULTS
During the study period, 79,686 cases were included in the analytic sample; 950 patients (1.2 %) had pre-existing coronary artery stents. <1 % of patients experienced MACE within 30 days following non-cardiac surgery (0.8 %). After confounder adjustment and propensity score matching, there were no statistically significant differences in MACE among racial and ethnic minority patients compared to NHW patients (OR = 0.77; 95 % CI: 0.48, 1.25). In our sensitivity analyses, stratifying by sex, there were no differences in MACE by race and ethnicity.
CONCLUSIONS CONCLUSIONS
The study found no statistically significant differences in MACE by race and ethnicity among patients who underwent non-cardiac surgery. Access to a high-volume, high-quality hospital such as the one studied may reduce the presence of healthcare disparities and may explain why our findings are not consistent with previous studies.

Identifiants

pubmed: 38876941
pii: S1553-8389(24)00534-7
doi: 10.1016/j.carrev.2024.06.004
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Informations de copyright

Copyright © 2024 Elsevier Inc. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Auteurs

Demian Herrera-Quiroz (D)

Mayo Clinic Alix School of Medicine, Mayo Clinic, Phoenix, AZ 85054, USA.

Bradford B Smith (BB)

Department of Anesthesiology and Perioperative Medicine, Mayo Clinic, Phoenix, AZ 85054, USA.

Christopher Dodoo (C)

Department of Quantitative Health Sciences, Mayo Clinic; Phoenix, AZ 85054, USA.

Michael J Brown (MJ)

Department of Anesthesiology and Perioperative Medicine, Mayo Clinic, Rochester, MN, USA.

Sharonne N Hayes (SN)

Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN, USA.

Adam J Milam (AJ)

Department of Anesthesiology and Perioperative Medicine, Mayo Clinic, Phoenix, AZ 85054, USA; Department of Quantitative Health Sciences, Mayo Clinic; Phoenix, AZ 85054, USA. Electronic address: milam.adam@mayo.edu.

Classifications MeSH