Antigenic CD4+ T Cell Marburg Virus Non-mutagenic Non-toxic and High world population coverage Peptide based vaccine

Journal

Journal of King Saud University. Science
ISSN: 2213-686X
Titre abrégé: J King Saud Univ Sci
Pays: Saudi Arabia
ID NLM: 9886378

Informations de publication

Date de publication:
Feb 2022
Historique:
medline: 1 2 2022
pubmed: 1 2 2022
entrez: 17 6 2024
Statut: ppublish

Résumé

Marburg, a RNA virus (MRV), is responsible for causing hemorrhagic fever that affects humans and non-human primates. World Health Organization (WHO), National Institutes of Health (NIH) and Centre of Disease Control and Prevention (CDC) considered this as an extremely dangerous virus, thus categorised as risk group 4, category A priority pathogen and category "A" bioterrorism agent, respectively. Despite of all these alarming concerns, no prophylaxis arrangements are available against this virus till date. In fact, the construction of immunogenic vaccine candidates by traditional molecular immunology methods is time consuming and very expensive. Considering these concerns, herein, we have designed CD4 + T Cell multiepitopes against MRV using

Identifiants

pubmed: 38881729
doi: 10.1016/j.jksus.2021.101751
pmc: PMC11178283
pii:
doi:

Types de publication

Journal Article

Langues

eng

Déclaration de conflit d'intérêts

Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Auteurs

Anupam Dhasmana (A)

Department of Immunology and Microbiology, School of Medicine, University of Texas Rio Grande Valley, Edinburg, TX, USA.
Department of Biosciences, Himalayan Institute of Medical Sciences, Swami Rama Himalayan University, Dehradun, India.

Swati Dhasmana (S)

Department of Immunology and Microbiology, School of Medicine, University of Texas Rio Grande Valley, Edinburg, TX, USA.

Ahmad Alsulimani (A)

Medical Laboratory Technology Department, College of Applied Medical Sciences, Jazan University, Jazan, Saudi Arabia.

Sudhir Kotnala (S)

Department of Immunology and Microbiology, School of Medicine, University of Texas Rio Grande Valley, Edinburg, TX, USA.

Vivek Kumar Kashyap (VK)

Department of Immunology and Microbiology, School of Medicine, University of Texas Rio Grande Valley, Edinburg, TX, USA.

Shafiul Haque (S)

Research and Scientific Studies Unit, College of Nursing and Allied Health Sciences, Jazan University, Jazan, Saudi Arabia.
Bursa Uludağ University, Faculty of Medicine, Görükle Campus, 16059 Nilüfer, Bursa, Turkey.

Meena Jaggi (M)

Department of Immunology and Microbiology, School of Medicine, University of Texas Rio Grande Valley, Edinburg, TX, USA.

Murali M Yallapu (MM)

Department of Immunology and Microbiology, School of Medicine, University of Texas Rio Grande Valley, Edinburg, TX, USA.

Subhash C Chauhan (SC)

Department of Immunology and Microbiology, School of Medicine, University of Texas Rio Grande Valley, Edinburg, TX, USA.

Classifications MeSH