C-3 alkoxymethylation of 4-oxo-1,4-dihydroquinoline 2-carboxylic acid esters

Esters of kynurenic acid, a known neuroprotective agent were reacted with cyclic amino acids to yield novel alkoxymethylated products under optimized reaction conditions. The importance of amino acid based (primary, secondary, biogenic and synthetic) organic additives was proven by the conduction of numerous test reactions. Thoroughly extended investigations, directly focusing on amino acid catalysis, which is an emerging and up-to-date field of catalysis and green chemical processes, have been conducted. The mechanism of the alkoxymethylation reaction was proposed and later the findings supported the hypothesis of the first

Informations de copyright

© 2024 The Authors.

Déclaration de conflit d'intérêts

The authors declare no conflict of interest.