Design, synthesis, and biological evaluation of multiple F-18 S1PR1 radiotracers in rodent and nonhuman primate.

Journal

Organic & biomolecular chemistry
ISSN: 1477-0539
Titre abrégé: Org Biomol Chem
Pays: England
ID NLM: 101154995

Informations de publication

Date de publication:
17 Jun 2024
Historique:
medline: 17 6 2024
pubmed: 17 6 2024
entrez: 17 6 2024
Statut: aheadofprint

Résumé

Here we report our design and synthesis of 28 new fluorine-containing compounds as potential F-18 radiotracers for CNS imaging of sphingosine-1-phosphate receptor 1 (S1PR1), and determination of their

Identifiants

DOI: 10.1039/d4ob00712c PMID: 38884683
pubmed: 38884683
doi: 10.1039/d4ob00712c
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Auteurs

Lin Qiu (L)

Department of Radiology, Washington University School of Medicine, St Louis, Missouri 63110, USA. zhudetu@wustl.edu.
ORCID: 0000-0001-8823-4132

Hao Jiang (H)

Department of Radiology, Washington University School of Medicine, St Louis, Missouri 63110, USA. zhudetu@wustl.edu.
ORCID: 0000-0002-8845-4378

Charles Zhou (C)

Department of Radiology, Washington University School of Medicine, St Louis, Missouri 63110, USA. zhudetu@wustl.edu.

Vijai Kumar Reddy Tangadanchu (VKR)

Department of Radiology, Washington University School of Medicine, St Louis, Missouri 63110, USA. zhudetu@wustl.edu.
ORCID: 0000-0003-4073-5362

Jinzhi Wang (J)

Department of Radiology, Washington University School of Medicine, St Louis, Missouri 63110, USA. zhudetu@wustl.edu.

Tianyu Huang (T)

Department of Radiology, Washington University School of Medicine, St Louis, Missouri 63110, USA. zhudetu@wustl.edu.
ORCID: 0000-0002-5607-4901

Robert J Gropler (RJ)

Department of Radiology, Washington University School of Medicine, St Louis, Missouri 63110, USA. zhudetu@wustl.edu.
ORCID: 0000-0002-6550-0570

Joel S Perlmutter (JS)

Department of Radiology, Washington University School of Medicine, St Louis, Missouri 63110, USA. zhudetu@wustl.edu.
Department of Neurology, Neuroscience, Physical Therapy and Occupational Therapy, Washington University School of Medicine, Saint Louis, Missouri, 63110, USA.
ORCID: 0000-0003-3263-8917

Tammie L S Benzinger (TLS)

Department of Radiology, Washington University School of Medicine, St Louis, Missouri 63110, USA. zhudetu@wustl.edu.
ORCID: 0000-0002-8114-0552

Zhude Tu (Z)

Department of Radiology, Washington University School of Medicine, St Louis, Missouri 63110, USA. zhudetu@wustl.edu.
ORCID: 0000-0003-0325-835X

Classifications MeSH