Review of chemical models and applications in Geant4-DNA: Report from the ESA BioRad III Project.
Geant4‐DNA
radiation chemistry
water radiolysis
Journal
Medical physics
ISSN: 2473-4209
Titre abrégé: Med Phys
Pays: United States
ID NLM: 0425746
Informations de publication
Date de publication:
18 Jun 2024
18 Jun 2024
Historique:
revised:
17
05
2024
received:
19
01
2024
accepted:
25
05
2024
medline:
18
6
2024
pubmed:
18
6
2024
entrez:
18
6
2024
Statut:
aheadofprint
Résumé
A chemistry module has been implemented in Geant4-DNA since Geant4 version 10.1 to simulate the radiolysis of water after irradiation. It has been used in a number of applications, including the calculation of G-values and early DNA damage, allowing the comparison with experimental data. Since the first version, numerous modifications have been made to the module to improve the computational efficiency and extend the simulation to homogeneous kinetics in bulk solution. With these new developments, new applications have been proposed and released as Geant4 examples, showing how to use chemical processes and models. This work reviews the models implemented and application developments for modeling water radiolysis in Geant4-DNA as reported in the ESA BioRad III Project.
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : ESA/BioRad3
ID : 4000132935/21/NL/CRS
Organisme : ESA/BioRad3
ID : NIH/NCI R01CA187003
Organisme : ESA/BioRad3
ID : R01CA266419
Informations de copyright
© 2024 American Association of Physicists in Medicine.
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