The Multifaceted Actions of PVP-Curcumin for Treating Infections.
Curcumin
/ pharmacology
Photosensitizing Agents
/ pharmacology
Rec A Recombinases
/ metabolism
Ciprofloxacin
/ pharmacology
Anti-Bacterial Agents
/ pharmacology
Photochemotherapy
/ methods
SOS Response, Genetics
/ drug effects
Escherichia coli K12
/ drug effects
Escherichia coli Proteins
/ metabolism
Povidone
/ chemistry
Microbial Sensitivity Tests
Escherichia coli
/ drug effects
Light
DNA-Binding Proteins
antimicrobial photodynamic therapy
antimicrobial resistance
bacterial SOS response
Journal
International journal of molecular sciences
ISSN: 1422-0067
Titre abrégé: Int J Mol Sci
Pays: Switzerland
ID NLM: 101092791
Informations de publication
Date de publication:
02 Jun 2024
02 Jun 2024
Historique:
received:
25
04
2024
revised:
23
05
2024
accepted:
29
05
2024
medline:
19
6
2024
pubmed:
19
6
2024
entrez:
19
6
2024
Statut:
epublish
Résumé
Curcumin is a natural compound that is considered safe and may have potential health benefits; however, its poor stability and water insolubility limit its therapeutic applications. Different strategies aim to increase its water solubility. Here, we tested the compound PVP-curcumin as a photosensitizer for antimicrobial photodynamic therapy (aPDT) as well as its potential to act as an adjuvant in antibiotic drug therapy. Gram-negative
Identifiants
pubmed: 38892328
pii: ijms25116140
doi: 10.3390/ijms25116140
pii:
doi:
Substances chimiques
Curcumin
IT942ZTH98
Photosensitizing Agents
0
Rec A Recombinases
EC 2.7.7.-
Ciprofloxacin
5E8K9I0O4U
Anti-Bacterial Agents
0
Escherichia coli Proteins
0
recA protein, E coli
0
Povidone
FZ989GH94E
DNA-Binding Proteins
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : Austrian Research Promotion Agency
ID : 900408