Novel 2,4-Dichloro-5-sulfamoylbenzoic Acid Oxime Esters: First Studies as Potential Human Carbonic Anhydrase Inhibitors.

Journal

ACS medicinal chemistry letters
ISSN: 1948-5875
Titre abrégé: ACS Med Chem Lett
Pays: United States
ID NLM: 101521073

Informations de publication

Date de publication:
13 Jun 2024
Historique:
received: 01 05 2024
revised: 18 05 2024
accepted: 21 05 2024
pmc-release: 13 06 2025
medline: 19 6 2024
pubmed: 19 6 2024
entrez: 19 6 2024
Statut: epublish

Résumé

In this study, a focused library of oxime ester derivatives of 2,4-dichloro-5-sulfamoylbenzoic acid (lasamide) containing Schiff bases was synthesized and tested

Identifiants

DOI: 10.1021/acsmedchemlett.4c00206 PMID: 38894925 PMC: PMC11181484
pubmed: 38894925
doi: 10.1021/acsmedchemlett.4c00206
pmc: PMC11181484
doi:

Types de publication

Journal Article

Langues

eng

Pagination

972-978

Informations de copyright

© 2024 American Chemical Society.

Déclaration de conflit d'intérêts

The authors declare no competing financial interest.

Auteurs

Jaydeo T Kilbile (JT)

Department of Chemistry, School of Basic and Applied Sciences, MGM University, Chhatrapati Sambhajinagar, 431003 Maharashtra, India.

Suryakant B Sapkal (SB)

Department of Chemistry, School of Basic and Applied Sciences, MGM University, Chhatrapati Sambhajinagar, 431003 Maharashtra, India.

Gioele Renzi (G)

NEUROFARBA Department, Sezione di Scienze Farmaceutiche e Nutraceutiche, University of Florence, Sesto Fiorentino, 50019 Florence, Italy.
ORCID: 0009-0008-9109-030X

Ilaria D'Agostino (I)

NEUROFARBA Department, Sezione di Scienze Farmaceutiche e Nutraceutiche, University of Florence, Sesto Fiorentino, 50019 Florence, Italy.
Department of Pharmacy, University of Pisa, 56126 Pisa, Italy.
ORCID: 0000-0002-4870-7326

Luigi Cutarella (L)

Department of Biotechnology, Chemistry and Pharmacy, University of Siena, 53100 Siena, Italy.

Mattia Mori (M)

Department of Biotechnology, Chemistry and Pharmacy, University of Siena, 53100 Siena, Italy.
ORCID: 0000-0003-2398-1254

Barbara De Filippis (B)

Department of Pharmacy "G. d'Annunzio", University of Chieti-Pescara, 66100 Chieti, Italy.

Imadul Islam (I)

King Abdullah International Medical Research Center (KAIMRC), King Saud Bin Abdulaziz University for Health Sciences, Ministry of National Guard-Health Affairs, Riyadh 14811, Saudi Arabia.

Maria Luisa Massardi (ML)

Department of Molecular and Translational Medicine, University of Brescia, 25123 Brescia, Italy.

Elena Somenza (E)

Department of Molecular and Translational Medicine, University of Brescia, 25123 Brescia, Italy.

Roberto Ronca (R)

Department of Molecular and Translational Medicine, University of Brescia, 25123 Brescia, Italy.

Yasinalli Tamboli (Y)

King Abdullah International Medical Research Center (KAIMRC), King Saud Bin Abdulaziz University for Health Sciences, Ministry of National Guard-Health Affairs, Riyadh 14811, Saudi Arabia.
ORCID: 0000-0002-5161-0170

Fabrizio Carta (F)

NEUROFARBA Department, Sezione di Scienze Farmaceutiche e Nutraceutiche, University of Florence, Sesto Fiorentino, 50019 Florence, Italy.
ORCID: 0000-0002-1141-6146

Claudiu T Supuran (CT)

NEUROFARBA Department, Sezione di Scienze Farmaceutiche e Nutraceutiche, University of Florence, Sesto Fiorentino, 50019 Florence, Italy.
ORCID: 0000-0003-4262-0323

Classifications MeSH