Diabetic myocardial disorder. A clinical consensus statement of the Heart Failure Association of the ESC and the ESC Working Group on Myocardial & Pericardial Diseases.

Cardiac abnormalities Diabetic myocardial disorder Heart failure Prevention Risk assessment Treatment Type 2 diabetes mellitus

Journal

European journal of heart failure
ISSN: 1879-0844
Titre abrégé: Eur J Heart Fail
Pays: England
ID NLM: 100887595

Informations de publication

Date de publication:
19 Jun 2024
Historique:
revised: 31 05 2024
received: 16 04 2024
accepted: 06 06 2024
medline: 19 6 2024
pubmed: 19 6 2024
entrez: 19 6 2024
Statut: aheadofprint

Résumé

The association between type 2 diabetes mellitus (T2DM) and heart failure (HF) has been firmly established; however, the entity of diabetic myocardial disorder (previously called diabetic cardiomyopathy) remains a matter of debate. Diabetic myocardial disorder was originally described as the occurrence of myocardial structural/functional abnormalities associated with T2DM in the absence of coronary heart disease, hypertension and/or obesity. However, supporting evidence has been derived from experimental and small clinical studies. Only a minority of T2DM patients are recognized as having this condition in the absence of contributing factors, thereby limiting its clinical utility. Therefore, this concept is increasingly being viewed along the evolving HF trajectory, where patients with T2DM and asymptomatic structural/functional cardiac abnormalities could be considered as having pre-HF. The importance of recognizing this stage has gained interest due to the potential for current treatments to halt or delay the progression to overt HF in some patients. This document is an expert consensus statement of the Heart Failure Association of the ESC and the ESC Working Group on Myocardial & Pericardial Diseases. It summarizes contemporary understanding of the association between T2DM and HF and discuses current knowledge and uncertainties about diabetic myocardial disorder that deserve future research. It also proposes a new definition, whereby diabetic myocardial disorder is defined as systolic and/or diastolic myocardial dysfunction in the presence of diabetes. Diabetes is rarely exclusively responsible for myocardial dysfunction, but usually acts in association with obesity, arterial hypertension, chronic kidney disease and/or coronary artery disease, causing additive myocardial impairment.

Identifiants

pubmed: 38896048
doi: 10.1002/ejhf.3347
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Informations de copyright

© 2024 European Society of Cardiology.

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Auteurs

Petar M Seferović (PM)

Faculty of Medicine, University of Belgrade, Belgrade, Serbia.
Serbian Academy of Sciences and Arts, Belgrade, Serbia.

Walter J Paulus (WJ)

Amsterdam University Medical Centers, Amsterdam, The Netherlands.

Giuseppe Rosano (G)

Department of Human Sciences and Promotion of Quality of Life, San Raffaele Open University of Rome, Rome, Italy.
Cardiology, San Raffaele Cassino Hospital, Cassino, Italy.

Marija Polovina (M)

Faculty of Medicine, University of Belgrade, Belgrade, Serbia.
Department of Cardiology, University Clinical Centre of Serbia, Belgrade, Serbia.

Mark C Petrie (MC)

School of Cardiovascular and Metabolic Health, University of Glasgow, Glasgow, UK.

Pardeep S Jhund (PS)

School of Cardiovascular and Metabolic Health, University of Glasgow, Glasgow, UK.

Carsten Tschöpe (C)

Berlin Institute of Health at Charité - Center for Regenerative Therapies, Universitätsmedizin Berlin, Berlin, Germany.
Deutsches Herzzentrum der Charité, Department of Cardiology (CVK) and German Centre for Cardiovascular Research (DZHK)- Partner Site Berlin, Charité Universitätsmedizin Berlin, Berlin, Germany.

Naveed Sattar (N)

School of Cardiovascular and Metabolic Health, University of Glasgow, Glasgow, UK.

Massimo Piepoli (M)

Cardiology University Department, RCCS Policlinico San Donato, San Donato Milanese, Italy.
Department of Biomedical Sciences for Health, University of Milan, Milan, Italy.

Zoltán Papp (Z)

Division of Clinical Physiology, Department of Cardiology, Faculty of Medicine, University of Debrecen, Debrecen, Hungary.

Eberhard Standl (E)

Diabetes Research Group e.V. at Munich Helmholtz Center, Munich, Germany.

Mamas A Mamas (MA)

Cardiovascular Research Group, Keele University, Keele, UK.

Paul Valensi (P)

Polyclinique d'Aubervilliers, Aubervilliers, and Paris Nord University, Bobigny, France.

Ales Linhart (A)

Department of Internal Medicine, School of Medicine, Charles University and General University Hospital, Prague, Czech Republic.

Nebojša Lalić (N)

Faculty of Medicine, University of Belgrade, Belgrade, Serbia.
Serbian Academy of Sciences and Arts, Belgrade, Serbia.
Department of Endocrinology, University Clinical Centre of Serbia, Belgrade, Serbia.

Antonio Ceriello (A)

IRCCS MultiMedica, Milan, Italy.

Wolfram Döhner (W)

Berlin Institute of Health at Charité - Center for Regenerative Therapies, Universitätsmedizin Berlin, Berlin, Germany.
Deutsches Herzzentrum der Charité, Department of Cardiology (CVK) and German Centre for Cardiovascular Research (DZHK)- Partner Site Berlin, Charité Universitätsmedizin Berlin, Berlin, Germany.
Center for Stroke Research Berlin (CSB), Charité Universitätsmedizin Berlin, Berlin, Germany.

Arsen Ristić (A)

Faculty of Medicine, University of Belgrade, Belgrade, Serbia.
Department of Cardiology, University Clinical Centre of Serbia, Belgrade, Serbia.

Ivan Milinković (I)

Faculty of Medicine, University of Belgrade, Belgrade, Serbia.
Department of Cardiology, University Clinical Centre of Serbia, Belgrade, Serbia.

Jelena Seferović (J)

Faculty of Medicine, University of Belgrade, Belgrade, Serbia.
Department of Endocrinology, University Clinical Centre of Serbia, Belgrade, Serbia.

Francesco Cosentino (F)

Unit of Cardiology, Karolinska Institute and Karolinska University Hospital, Stockholm, Sweden.

Marco Metra (M)

Institute of Cardiology, ASST Spedali Civili, Department of Medical and Surgical Specialties, Radiological Sciences and Public Health, University of Brescia, Brescia, Italy.

Andrew J S Coats (AJS)

Heart Research Institute, Sydney, NSW, Australia.

Classifications MeSH